Skip to content

The effect of the two drugs( Sodium Thiopental or Ketamine) duration and after ECT

Comparison of changes in blood pressure and heart rate ;following the use of Sodium Thiopental or Ketamine duration and after ECT

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016030726950N1
Enrollment
64
Registered
2016-06-20
Start date
2015-11-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Succinylcholine Chloride. Condition 2: Sodium Thiopental. Condition 3: Ketamine. Poisoning: Skeletal muscle relaxants [neuromuscular blocking agents], Skeletal muscle relaxants [neuromuscular blocking agents] Poisoning:Intravenous anaesthetics Poisoning: Other and unspecified general anaesthetics

Interventions

Intervention 1: First group received A packages included succinylcholine (0.5 mg/kg) and Sodium thiopental (2 mg/kg).Drugs inject IV and bolusly. Intervention 2: Second group received B packages incl
Treatment - Drugs
First group received A packages included succinylcholine (0.5 mg/kg) and Sodium thiopental (2 mg/kg).Drugs inject IV and bolusly.
Second group received B packages included succinylcholine (0.5 mg/kg) and Ketamine (1mg/kg).Drugs inject IV and bolusly.

Sponsors

Vice Chancellor for Research of Isfahan University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 25 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients candidates receiving electroconvulsive therapy seizures; Subjects younger than 25 years old with American society of anesthesiology physical status class 1 (ASAI) . Exclusion criteria: After receiving the shock, hemodynamic unstable.; patients with seizure duration more than 90 seconds less than 20 seconds;After receiving the shock? tracheal intubation indicated; drugs used to react strongly.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Back to Breathe Spontaneously. Timepoint: From the end of seizure to respiration. Method of measurement: Second with Timer.;Seizure Duration. Timepoint: From the start to the end of seizure. Method of measurement: Second with Timer.;Blood Pressure. Timepoint: 1, 5 and 10 seconds after the shock. Method of measurement: mmhg with Manometer.;Pulse. Timepoint: 1, 5 and 10 seconds after the shock. Method of measurement: Beat per minute with Pulse Oximeter.;O2 saturation. Timepoint: 1, 5 and 10 seconds after the shock. Method of measurement: Percent with Pulse Oximeter.;Recovery Duration. Timepoint: From the end of seizure to full consciousness. Method of measurement: Minute with Timer.

Secondary

MeasureTime frame
Headache. Timepoint: After recovery. Method of measurement: Ask the patient.;Cough. Timepoint: After recovery. Method of measurement: Ask the patient.;Nausea and Vomiting. Timepoint: After recovery. Method of measurement: Ask the patient.;Laryngospasm. Timepoint: After recovery. Method of measurement: Evaluation of patient such as breathing and o2 sat.;Muscle Pain. Timepoint: After recovery. Method of measurement: Ask the patient.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026