Acne. Acne, unspecified
Conditions
Interventions
Cinnamon essential oil (maximum 1%) in a topical formulation will apply on acne, two times a day (morning and night), for 8 weeks.
Treatment - Drugs
Cinnamon essential oil (maximum 1%) in a topical formulation will apply on acne, two times a day (morning and night), for 8 weeks
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 58 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age of 20-58 years; Mild to Moderate Acne affection, without cystic acne; having at least 15 inflamed and 15 non-inflamed acne lesions on the face. Exclusion criteria: History of acute disease of patient or any type of sensitivity or allergy to the components of medication; Using topical anti-acne medications which include vitamin A, Alpha or Beta-hydroxy acids, Retin A, Antibiotics or benzoyl peroxide during 4 weeks before the beginning of intervention; Using oral antibiotics for treating acne during 1 month before the beginning of intervention; Using systemic isotretinoin or application of laser therapy, microdermabrasion and chemical peeling during 6 month before the beginning of intervention; Pregnant or Lactating women; Women who want to be pregnant in the next 6 month after the beginning of intervention; Patients who are exposed to long-term and direct sunlight or UV lamps, without skin protection, due to their occupation; Patients who do not follow the protocol of treatment.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin erythema. Timepoint: Before intervention, 4 weeks after the beginning of intervention and 8 weeks after the beginning of intervention. Method of measurement: Mexameter.;PH. Timepoint: Before intervention, 4 weeks after the beginning of intervention and 8 weeks after the beginning of intervention. Method of measurement: pH-meter.;Skin hydration. Timepoint: Before intervention, 4 weeks after the beginning of intervention and 8 weeks after the beginning of intervention. Method of measurement: Corneometer.;Change in sebum production. Timepoint: Before intervention, 4 weeks after the beginning of intervention and 8 weeks after the beginning of intervention. Method of measurement: Sebumeter.;Trans Epidermal Water Loss (TEWL). Timepoint: Before intervention, 4 weeks after the beginning of intervention and 8 weeks after the beginning of intervention. Method of measurement: TEWAmeter.;Skin marks. Timepoint: Before intervention, 4 weeks after the beginning of intervention and 8 weeks after the beginning of intervention. Method of measurement: Skin surface analyzer.;Acne lesion and presence of Propionibacterium acnes bacteria. Timepoint: Before intervention, 4 weeks after the beginning of intervention and 8 weeks after the beginning of intervention. Method of measurement: Visiopor.;Number of Comedones. Timepoint: Before intervention, 4 weeks after the beginning of intervention and 8 weeks after the beginning of intervention. Method of measurement: Clinical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahdi Vazirian
Tehran University of Medical Sciences
Outcome results
None listed