The effect of the two drugs propofol-remifentanil and ketofol in electroconvulsive therapy

Comparison between the effects of propofol-remifentanil and ketofol on seizure duration in electroconvulsive therapy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160307026950N9

Enrollment

Registered

2019-03-18

Start date

2018-03-21

Completion date

Unknown

Last updated

2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Seizure duration.

Interventions

Intervention 1: Intervention group A: Initially, personal consent is obtained from the patients. Then the patient is placed on the operating bed and standard monitoring devices including pulsoximetry,

Eligibility

Sex/Gender

All

Age

6 Years to 25 Years

Inclusion criteria

Inclusion criteria: Patients candidates receiving electroconvulsive therapy seizures Patients older than 6 yeras old and younger than 25 years old Patients with American society of anesthesiology physical status class 1,2 (ASAI,II)

Exclusion criteria

Exclusion criteria: Severe cardiovascular disease Severe respiratory disease Severe kidney disease Severe Liver disease drugs Allergy

Design outcomes

Primary

Measure	Time frame
Seizure duration. Timepoint: After intervention. Method of measurement: In seconds using a chornometer.;Heart rate changes. Timepoint: Before the intervention, 1 , 5, 10 minutes after intervention and After The discharge time of recovery. Method of measurement: Pulse oximetry device.;Mean arterial blood pressure. Timepoint: Before the intervention, 1 , 5, 10 minutes after intervention and After The discharge time of recovery. Method of measurement: Non invasive blood pressure.;Oxygen saturation. Timepoint: Before the intervention, 1 , 5, 10 minutes after intervention and After The discharge time of recovery. Method of measurement: Pulse oximetry device.;Recovery Duration. Timepoint: From the end of seizure to full consciousness. Method of measurement: Minute with using a chronometer.	—

Measure

Time frame

Seizure duration. Timepoint: After intervention. Method of measurement: In seconds using a chornometer.;Heart rate changes. Timepoint: Before the intervention, 1 , 5, 10 minutes after intervention and After The discharge time of recovery. Method of measurement: Pulse oximetry device.;Mean arterial blood pressure. Timepoint: Before the intervention, 1 , 5, 10 minutes after intervention and After The discharge time of recovery. Method of measurement: Non invasive blood pressure.;Oxygen saturation. Timepoint: Before the intervention, 1 , 5, 10 minutes after intervention and After The discharge time of recovery. Method of measurement: Pulse oximetry device.;Recovery Duration. Timepoint: From the end of seizure to full consciousness. Method of measurement: Minute with using a chronometer.

—

Secondary

Measure	Time frame
Nausea and Vomiting. Timepoint: After end of the seizure. Method of measurement: Questionnaire.;Laryngospasm. Timepoint: After end of the seizure. Method of measurement: Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShirin hashemi fesharaki

Esfahan University of Medical Sciences

shhashemif@yahoo.com+98 31 3229 5695

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026