Comparing the effect of intramuscular methadone VS. intramuscular meperidine on pain after spinal anesthesia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160307026950N76

Enrollment

Registered

2026-01-10

Start date

2026-01-21

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

??? ?????? ?? ?? ??? ?????. Encounter for cesarean delivery without indication

Interventions

Intervention 1: Intervention group: Initial dose of 5 mg/kg methadone intramuscularly immediately after the end of surgery. Intervention 2: Intervention group: Initial dose of 25 mg/kg meperidine intr

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Pregnant women undergoing elective cesarean section Age between 18 to 45 Informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Heart, kidney, and lung diseases Mental disorders, Diabetes mellitus Thyroid disorder History of alcohol and opioid addiction Use of interfering medications, including labor pain medications Need for repeated blood transfusions during surgery

Design outcomes

Primary

Measure	Time frame
Pain score in a Likert scale questionnaire. Timepoint: Pain intensity at 0-2-4-6-12-24 hours after surgery. Method of measurement: Questionnaire with Likert scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtena Farangi

Esfahan University of Medical Sciences

atena.fa.00@gmail.com+98 991 277 0784

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026