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Effect of gargling rosemary extract and Ketamine on hoarseness and sore throat

Comparison of the effect of gargling rosemary extract and Ketamine on hoarseness and sore throat after tracheal intubation

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160307026950N50
Enrollment
120
Registered
2023-01-01
Start date
2022-12-22
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sore throat and Hoarseness after endotracheal intubation.

Interventions

Intervention 1: Intervention group A: In this group of patients, before induction of anesthesia, 30 drops of Rosemary solution (manufactured by Fadek Sepahan Pharmaceutical Company) dissolved in 30 ml

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients 18 to 65 years old Anesthesia class I and II according to ASA criteria Candidate for general anesthesia with tracheal intubation Informed consent to enter the study

Exclusion criteria

Exclusion criteria: Addiction to cigarettes and drugs Allergic to rosemary and Ketamine Diabetes Asthma and airway problems

Design outcomes

Primary

MeasureTime frame
Severity of sore throat. Timepoint: 1 hour after recovery and 6, 12, 24 and 48 hours after that. Method of measurement: Scoring from 0 to 10 based on pain intensity.;Severity of hoarseness. Timepoint: 1 hour after recovery and 6, 12, 24 and 48 hours after that. Method of measurement: Scoring from 0 to 3 based on the severity of hoarseness.

Secondary

MeasureTime frame
Blood Pressure. Timepoint: From the time of induction of anesthesia until the end of recovery. Method of measurement: sphygmomanometer.;Heart Rate. Timepoint: From the time of induction of anesthesia until the end of recovery. Method of measurement: Electrocardiogram.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRoza Bidkalameh

Esfahan University of Medical Sciences

rozabidkalame94@gmail.com+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026