The effect of Succinylcholine on the hemodynamic status in ECT patients

Comparison of the effect of injection of 0.3 (mg/kg) and 0.6 (mg/kg) Succinylcholine on the hemodynamic status of patients undergoing electroconvulsive therapy

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160307026950N40

Enrollment

Registered

2022-06-11

Start date

2022-06-22

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Electroconvulsive Therapy. Epilepsy and recurrent seizures

Interventions

Intervention 1: Intervention group 1: In this group, after lying on the bed and monitoring connection, patients received 5 mg/kg Sodium Thiopental from Jaber Ibn Hayyan company and 0.3 mg/kg Succinylc

Eligibility

Sex/Gender

All

Age

9 Years to 25 Years

Inclusion criteria

Inclusion criteria: age 9 to 25 years candidate for ECT under general anesthesia ASA class I and II informed consent to enter the study

Exclusion criteria

Exclusion criteria: Alcohol and drug addiction History of seizures or epilepsy Allergy to anesthetics Heart, nerve and muscle diseases

Design outcomes

Primary

Measure	Time frame
Heart Rate. Timepoint: Before anesthesia, 1 minute after Succinylcholine injection, 1,3,5 minutes after seizures and then every 5 minutes to 20 minutes after seizures. Method of measurement: Electrocardiogram.;Blood Pressure. Timepoint: Before anesthesia, 1 minute after Succinylcholine injection, 1 minute after seizures and then every 5 minutes to 20 minutes after seizures. Method of measurement: Barometer.;O2 Saturation. Timepoint: Before anesthesia, 1 minute after Succinylcholine injection, 1,3,5 minutes after seizures and then every 5 minutes to 20 minutes after seizures. Method of measurement: Pulse Oximeter.	—

Measure

Time frame

Heart Rate. Timepoint: Before anesthesia, 1 minute after Succinylcholine injection, 1,3,5 minutes after seizures and then every 5 minutes to 20 minutes after seizures. Method of measurement: Electrocardiogram.;Blood Pressure. Timepoint: Before anesthesia, 1 minute after Succinylcholine injection, 1 minute after seizures and then every 5 minutes to 20 minutes after seizures. Method of measurement: Barometer.;O2 Saturation. Timepoint: Before anesthesia, 1 minute after Succinylcholine injection, 1,3,5 minutes after seizures and then every 5 minutes to 20 minutes after seizures. Method of measurement: Pulse Oximeter.

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Secondary

Measure	Time frame
Duration of seizures. Timepoint: From the beginning of the seizure (tonic) to the end of the motor seizure (clonic). Method of measurement: Clock (minute, second).;Recovery duration. Timepoint: From the end of clonic movements to complete awakening. Method of measurement: Clock.;Nausea and vomiting. Timepoint: From the return of motor reflexes up to 1 hour. Method of measurement: Observation.;Laryngospasm. Timepoint: From the time of extubation to the end of recovery. Method of measurement: Observation.	—

Measure

Time frame

Duration of seizures. Timepoint: From the beginning of the seizure (tonic) to the end of the motor seizure (clonic). Method of measurement: Clock (minute, second).;Recovery duration. Timepoint: From the end of clonic movements to complete awakening. Method of measurement: Clock.;Nausea and vomiting. Timepoint: From the return of motor reflexes up to 1 hour. Method of measurement: Observation.;Laryngospasm. Timepoint: From the time of extubation to the end of recovery. Method of measurement: Observation.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSorush Fatemi Naeini

Esfahan University of Medical Sciences

s.fnaini@gmail.com+98 31 3662 0048

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026