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The effect of Atropine-Neostigmine mixture and Ondansetron on headache after Cesarean section under spinal anesthesia

Comparison of the effectiveness of Atropine-Neostigmine mixture and Ondansetron injection in preventing headache after Cesarean section under spinal anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160307026950N39
Enrollment
60
Registered
2022-01-13
Start date
2022-01-21
Completion date
Unknown
Last updated
2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Headache after spinal anesthesia in cesarean. Complications of anesthesia during pregnancy

Interventions

Intervention 1: Intervention group A: In this group, eligible patients, after being placed on a surgical bed and monitoring connection, receive about 2cc/kg/hr serum 1/3-2/3 then 10µg/kg Atropine and

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Pregnant woman candidate for cesarean section under spinal anesthesia Age 18 to 45 years ASA class I and II Patient consent to study

Exclusion criteria

Exclusion criteria: Consumption of anticoagulants Existence of nerve damage in limbs, spine and CNS Having coagulation diseases History of spinal surgery, spinal stenosis and MS Having heart conduction disorders Have a history of migraine headaches

Design outcomes

Primary

MeasureTime frame
The headache after spinal anesthesia in Cesarean. Timepoint: Patients are followed up for headaches for up to seven days after the spinal block. In case of headache in the first 24 hours every 6 hours and then daily, its amount is measured by VAS scale. Method of measurement: VAS Pain Intensity Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehzad Nazemroaya

Esfahan University of Medical Sciences

b.nazemroaya@khuisf.ac.ir+98 31 3224 7233

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026