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The effect of Ondansetron on pain caused by Etomidate injection

Comparison of the effects of preventive injection of 4 mg and 8 mg Ondansetron doses on pain caused by Etomidate injection in patients under general anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160307026950N38
Enrollment
60
Registered
2021-10-25
Start date
2021-10-23
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain caused by Etomidate.

Interventions

Intervention 1: Intervention group A: In this group, eligible patients, after being placed on a surgical bed and monitoring connection, receive 300 ml of normal saline per hour, then they are injected

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients 18 to 60 years Grade I and II in ASA criteria (American Society of Anesthesia) Candidate for general anesthesia with Etomidate

Exclusion criteria

Exclusion criteria: Patients with Heart Disease Patients with Psychologic disease Allergic to drugs used in the study Taking sedatives or painkillers 24 hours before anesthesia Addiction to drugs

Design outcomes

Primary

MeasureTime frame
The amount of pain caused by Etomidate injection. Timepoint: During the injection until 30 seconds. Method of measurement: Faces Pain Rating Scale (FPRS).

Secondary

MeasureTime frame
Heart Rate. Timepoint: Before injection, immediately after injection, 5 and 10 minutes after Etomidate injection and then every 15 minutes until the end of the operation. Method of measurement: ECG monitoring.;Moderate arterial blood pressure. Timepoint: Before injection, immediately after injection, 5 and 10 minutes after Etomidate injection and then every 15 minutes until the end of the operation. Method of measurement: Barometer.;Arterial blood oxygen saturation. Timepoint: Before injection, immediately after injection, 5 and 10 minutes after Etomidate injection and then every 15 minutes until the end of the operation. Method of measurement: Pulse oximeter.;Duration of anesthesia. Timepoint: From the beginning of anesthesia to the end of recovery. Method of measurement: Clock.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRuzbeh Akhavanfar

Esfahan University of Medical Sciences

Roozbeh1372@gmail.com+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026