The effects of two different doses dexmedetomidine after Endotracheal intubation

Comparison of the effects of two different doses intranasal Dexmedetomidine on heart rate and blood pressure changes after Laryngoscopy and Endotracheal intubation in patients need of anesthesia before surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160307026950N15

Enrollment

Registered

2019-07-24

Start date

2018-03-21

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Blood pressure. Condition 2: Heart rate. Elevated blood-pressure reading, without diagnosis of hypertension Tachycardia, unspecified

Interventions

Intervention 1: Intervention group A:Initially , informed consent is obtained from the patients. After placing the patients on the operating bed, inclusion of standard monitoring including pulsoximetr

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients candidate Laryngoscopy and Endotracheal intubation Patients older than 18 yeras old and younger than 65 years old Patients with American society of anesthesiology physical status class 1,2 (ASAI,II)

Exclusion criteria

Exclusion criteria: Head and neck masses Airway malformation Uncontrollable blood pressure(More than 180/110) History of cardiovascular disease History of respiratory disease allergies to the drugs studied Body Mass Index greater than 30(BMI>30)

Design outcomes

Primary

Measure	Time frame
Heart rate changes. Timepoint: Before the intervention, 1 ,3, 5, 10 minutes after laryngoscopy. Method of measurement: Heart monitoring.;Systolic blood pressure. Timepoint: Before the intervention, 1 ,3, 5, 10 minutes after laryngoscopy. Method of measurement: Non invasive blood pressure monitor.;Diastolic blood pressure. Timepoint: Before the intervention, 1 ,3, 5, 10 minutes after laryngoscopy. Method of measurement: Non invasive blood pressure monitor.;Mean arterial pressure. Timepoint: Before the intervention, 1 ,3, 5, 10 minutes after laryngoscopy. Method of measurement: Non invasive blood pressure monitor.;Oxygen saturation. Timepoint: Before the intervention, 1 ,3, 5, 10 minutes after laryngoscopy. Method of measurement: Percent with pulse oximeter.;Recovery time. Timepoint: From the end of surgery to full consciousness. Method of measurement: Minute with using a chornometer.	—

Measure

Time frame

Heart rate changes. Timepoint: Before the intervention, 1 ,3, 5, 10 minutes after laryngoscopy. Method of measurement: Heart monitoring.;Systolic blood pressure. Timepoint: Before the intervention, 1 ,3, 5, 10 minutes after laryngoscopy. Method of measurement: Non invasive blood pressure monitor.;Diastolic blood pressure. Timepoint: Before the intervention, 1 ,3, 5, 10 minutes after laryngoscopy. Method of measurement: Non invasive blood pressure monitor.;Mean arterial pressure. Timepoint: Before the intervention, 1 ,3, 5, 10 minutes after laryngoscopy. Method of measurement: Non invasive blood pressure monitor.;Oxygen saturation. Timepoint: Before the intervention, 1 ,3, 5, 10 minutes after laryngoscopy. Method of measurement: Percent with pulse oximeter.;Recovery time. Timepoint: From the end of surgery to full consciousness. Method of measurement: Minute with using a chornometer.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Mohammad Ataie

Esfahan University of Medical Sciences

amir.ataie17@gmail.com+98 31 3222 8461

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026