Effects of two different doses of labetalol on electroconvulsive therapy in two groups of patients

A comparative study of heart rate and blood pressure changes during and after electroconvulsive therapy followed by two different doses of labetalol in two groups of patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160307026950N11

Enrollment

Registered

2019-05-27

Start date

2018-03-21

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart rate and blood pressure.

Interventions

Intervention 1: Intervention group A: Initially, personal consent is obtained from the patients. Then the patient is placed on the operating bed and standard monitoring devices including pulsoximetry,

Eligibility

Sex/Gender

All

Age

6 Years to 25 Years

Inclusion criteria

Inclusion criteria: patients candidates receiving electroconvulsive therapy Subjects older than 6 yeras old and younger than 25 years old American society of anesthesiology physical status class 1,2 (ASAI,II)

Exclusion criteria

Exclusion criteria: Severe cardiovascular disease Severe respiratory disease Severe kidney disease Severe Liver disease Drugs Allergy

Design outcomes

Primary

Measure	Time frame
Heart rate changes. Timepoint: Before the intervention, 1 , 5, 10 minutes after intervention and then After The discharge time of recovery. Method of measurement: Pulse oximetry device.;Mean arterial blood pressure. Timepoint: Before the intervention,1 , 5, 10 minutes after intervention and then After The discharge time of recovery. Method of measurement: Non invasive blood pressure.;Oxygen saturation. Timepoint: Before the intervention, 1 , 5, 10 minutes after intervention and then After The discharge time of recovery. Method of measurement: Pulse oximetry device.	—

Measure

Time frame

Heart rate changes. Timepoint: Before the intervention, 1 , 5, 10 minutes after intervention and then After The discharge time of recovery. Method of measurement: Pulse oximetry device.;Mean arterial blood pressure. Timepoint: Before the intervention,1 , 5, 10 minutes after intervention and then After The discharge time of recovery. Method of measurement: Non invasive blood pressure.;Oxygen saturation. Timepoint: Before the intervention, 1 , 5, 10 minutes after intervention and then After The discharge time of recovery. Method of measurement: Pulse oximetry device.

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Secondary

Measure	Time frame
Nausea and Vomiting. Timepoint: After end of the siezure. Method of measurement: Questionnaire.;Laryngospasm. Timepoint: After end of the siezure. Method of measurement: Questionnaire.;Duration of seizure. Timepoint: After intervention. Method of measurement: In seconds using a chornometer.;Recovery duration. Timepoint: From the end of seizure to full consciousness. Method of measurement: Minute with using a chornometer.	—

Measure

Time frame

Nausea and Vomiting. Timepoint: After end of the siezure. Method of measurement: Questionnaire.;Laryngospasm. Timepoint: After end of the siezure. Method of measurement: Questionnaire.;Duration of seizure. Timepoint: After intervention. Method of measurement: In seconds using a chornometer.;Recovery duration. Timepoint: From the end of seizure to full consciousness. Method of measurement: Minute with using a chornometer.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNegar Rezaei

Esfahan University of Medical Sciences

negarrezaei968@gmail.com+98 31 3666 0225

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026