Condition 1: cardiovascular disease. Condition 2: apnoea. Cardiovascular accident NOS Sleep apnoea
Conditions
Interventions
Patients will be treated for for six months with continuous positive pressure conditioning.
Treatment - Devices
Patients will be treated for for six months with continuous positive pressure conditioning
Sponsors
Vice Chancellor for research of Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
25 Years to 60 Years
Inclusion criteria
Inclusion criteria: Disorders are usually related with sleep apnea in patients with cardiovascular problems. Objectives: To determine the effect of continuous positive pressure ventilation on left ventricular diastolic function in patients with obstructive sleep apnea is. Design: This study is a clinical trial. Material and Method: In this study, 32 patients with concurrently obstructive sleep apnea and left ventricular diastolic dysfunction Inclusion criteria: echocardiographic evidence of left ventricular diastolic function disorder; Patients who used continuous positive pressure ventilation for at least an hour to be endured; During the four weeks before starting treatment, the patient does not any changes in the clinical comorbidity. During the four weeks prior to treatment, there is no change in the patient's medications; Young and middle-aged adults. Exclusion criteria: patients who are symptomatic obstructive sleep apnea; Morbid obesity, pregnant or breast feeding women; subjects who had severe heart disease during the past three months; Use less than 3/30 hours of continuous positive pressure ventilation during the night; During the six-month period of treatment, the patient is given a change in medication; Will be Checked by random sampling. Interventions: based on the results of polysomnography and echocardiography of patients underwent a six-month period conditioning continuous positive pressure fall and after completion of the course of treatment again groups, before and after 6 months of diastolic function of the left ventricle echocardiography
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peak E. Timepoint: 6 Months after treatment with continuous positive pressure ventilation. Method of measurement: Based on the grading echocardiography.;Peak A. Timepoint: 6 Months after treatment with continuous positive pressure ventilation. Method of measurement: Based on the grading echocardiography.;E/A Parameter. Timepoint: 6 Months after treatment with continuous positive pressure ventilation. Method of measurement: Based on the grading echocardiography.;Flow propagation velocity. Timepoint: 6 Months after treatment with continuous positive pressure ventilation. Method of measurement: Based on the grading echocardiography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Ali Yousefi
Isfahan University of Medical Sciences
Outcome results
None listed