Irritable Bowel Syndrome (IBS). Irritable bowel syndrome
Conditions
Interventions
Intervention 1: Intervention group: Oral prescription of a 100 mg capsule containing hydroalcoholic extract of Ajwain fruit, equal to 3 g of it and 400 mg auxiliary ingredients including lactose powd
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Adherence to diagnostic criteria of Irritable Bowel Syndrome (IBS) including recurrent abdominal pain at least three days in a month during past three months and beginning of symptoms at least from six months ago plus at least two conditions of three pain alleviation conditions after defecation, variations in number of defecation times and changes in stool consistency Age range of 18-70 years old Signing the informed consent
Exclusion criteria
Exclusion criteria: Being afflicted with any underlying disease pregnancy Being allergic to Apiaceae family plants Bowel dysfunctions including abnormal colonoscopy observations Lactation period Consumption of medications for improvement of irritable bowel syndrome symptoms
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abdominal pain. Timepoint: After intervention (one month after intervention). Method of measurement: Scoring patients based on a 0-10 Likert Scale with regard to improvements in symptoms (0=no improvement; 10= complete improvement).;Diarrhea. Timepoint: After intervention (one month after intervention). Method of measurement: Scoring patients based on a 0-10 Likert Scale with regard to improvements in symptoms (0=no improvement; 10= complete improvement).;Constipation. Timepoint: After intervention (one month after intervention). Method of measurement: Scoring patients based on a 0-10 Likert Scale with regard to improvements in symptoms (0=no improvement; 10= complete improvement).;Bloating. Timepoint: After intervention (one month after intervention). Method of measurement: Scoring patients based on a 0-10 Likert Scale with regard to improvements in symptoms (0=no improvement; 10= complete improvement). | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life score. Timepoint: Before intervention, 2 weeks after intervention, 4 weeks after study being initiated, 2 weeks after termination of the intervention. Method of measurement: Completing 34-item questionnaire of life quality among IBS patients (IBS_QOL34) by the patient himself. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahdi Vazirian
Tehran University of Medical Sciences
Outcome results
None listed