Comparing the effectiveness of the combination of caffeine, L-theanine and piperin compared to placebo and pure caffeine in increasing attention

Investigating the effectiveness of capsules containing the combination of caffeine, L-theanine and piperin compared to pure caffeine and placebo in improving attention in healthy people

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160306026938N19

Enrollment

Registered

2024-02-19

Start date

2024-02-14

Completion date

Unknown

Last updated

2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention and concentration deficit. Attention and concentration deficit

Interventions

Intervention 1: Intervention group: will receive 1- Caffeine capsule containing 200 milligrams of pure caffeine, 2- placebo (containing 300 mg starch) and 3- Caffeine + theanine + piperine capsule, co

Eligibility

Sex/Gender

All

Age

19 Years to 45 Years

Inclusion criteria

Inclusion criteria: Regular consumption of tea or coffee (at least five cups per week) Regular consumption of breakfast Normal or corrected-to-normal vision Body mass index between 20 and 30

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding Having acute diseases (infectious or non-infectious) Suffering from incurable chronic diseases such as cancer or types of epilepsy Deficiency of immune system Smoking

Design outcomes

Primary

Measure	Time frame
Total attention score. Timepoint: Measuring attention at the beginning of the study (before the start of the intervention) and half an hour after taking the drug or placebo. Method of measurement: Integrated Visual and Auditory Continuous Performance Test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdi Vazirian

Tehran University of Medical Sciences

Vazirian_m@tums.ac.ir+98 21 6412 1223

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026