effect of Quercus brantii and Myrtus communis suppository on women infection

A vaginal dosage form preparation of Gall and Myrtle and study of theirs effects in bacterial vaginitis via double blind randomized clinical trial with placebo control

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016030526917N1

Enrollment

100

Registered

2016-05-16

Start date

2016-09-19

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bactrial Vaginitis. Other specified inflammation of vagina and vulva

Interventions

Intervention 1: Suppositories prepared from the leaves of oak,For 16 nights. Intervention 2: One placebo suppository,.

Treatment - Drugs

Placebo

Suppositories prepared from the leaves of oak,For 16 nights

One placebo suppository,

Eligibility

Sex/Gender

Female

Age

77 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Women aged 18-55 years, with signs on physical examination and tests, The lack of recent use of antiparasitic drugs, antibiotics,immunosuppressive drugs and drugs during the past two weeks vaginal, No intercourse and no use of douching in last 48 hours, Lack of abnormal uterine bleeding, Non-pregnant and non-lactating, Not using douches repeatedly, No smoking or alcohol consumption and coumarin anticoagulants, Lack of sensitivity to drug components exclusion criteria: Taking any medication affecting drugs, Taking any drug effect on symptoms and treatment of vaginitis, Drug allergy, People who are considered patient based on the clinical diagnosis but based on test results are negative

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Check cluecells. Timepoint: 0, 16th, 45th after intervention. Method of measurement: counting by microscope.;Determination the PpH of vagina. Timepoint: 0, 16th, 45th after intervention. Method of measurement: by litmus paper with high precision.;Whiff test. Timepoint: 0, 16th, 45th after intervention. Method of measurement: The smell of ammonia or fish from the discharge after the addition of KOH 10%.;Discharge color. Timepoint: 0, 16th, 45th after intervention. Method of measurement: On examination it becomes clear to the eye.;Nugnet score. Timepoint: 0, 16th, 45th after intervention. Method of measurement: Using microbial count and Grading.	—

Measure

Time frame

Check cluecells. Timepoint: 0, 16th, 45th after intervention. Method of measurement: counting by microscope.;Determination the PpH of vagina. Timepoint: 0, 16th, 45th after intervention. Method of measurement: by litmus paper with high precision.;Whiff test. Timepoint: 0, 16th, 45th after intervention. Method of measurement: The smell of ammonia or fish from the discharge after the addition of KOH 10%.;Discharge color. Timepoint: 0, 16th, 45th after intervention. Method of measurement: On examination it becomes clear to the eye.;Nugnet score. Timepoint: 0, 16th, 45th after intervention. Method of measurement: Using microbial count and Grading.

—

Secondary

Measure	Time frame
Microbial count for Candida albicans? Gardnerella morphotype?Mycoplasma hominis? Ureaplasma urealyticum? Trichomonas vaginalis. Timepoint: 0, 16th, 45th after intervention. Method of measurement: counting by microscope.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Sayede Fatemeh Askari

Traditional Persian Pharmacy Department, Faculty of Pharmacy, Shiraz University of Medical Sciences

stud0653219921@sums.ac.ir+98 71 3242 4128

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026