Antioxidants in athletes

Effect of antioxidant rich formula supplementation and aerobic training on glutathione peroxidase and superoxide dismutase activity, determination of HSP-70 expressing mRNA and oxidative stress in female athletes

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016030526909N1

Enrollment

Registered

2016-04-10

Start date

2016-04-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General health of athletes. Routine general health check-up of sports teams

Interventions

Intervention 1: Antioxidant rich formula made of local materials. Intervention 2: Semi formula with similar appearance.

Antioxidant rich formula made of local materials

Semi formula with similar appearance

Eligibility

Sex/Gender

Female

Age

75 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 20-30 years old recreational healthy female athletes; without cardiovascular disease and muscular damage; and have normal blood pressure. Exclusion criteria: Weight loss or any special diet such as vegetarian diet over the past three month; consumption of any sport supplements such as creatine, Amino acids or protein or vitamin and mineral supplements and anti-inflammatory drugs 8 weeks prior the study; having acute and chronic illnesses; high fasting blood sugar or abnormal lipid profile; anemia; hormonal disorders and a BMI less than 18.5 or above 24.9

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Total antioxidant capacity (TAC). Timepoint: 6 times: 3 times before the intervention (before, 1 hour and 24 hours after exercise test) and 3 times post intervention (before, 1 hour and 24 hours after exercise test). Method of measurement: Specific kit.;Malondialdehyde (MDA). Timepoint: 6 times: 3 times before the intervention (before, 1 hour and 24 hours after exercise test) and 3 times post intervention (before, 1 hour and 24 hours after exercise test). Method of measurement: Specific kit.;Super oxide dismutase (SOD) activity. Timepoint: 6 times: 3 times before the intervention (before, 1 hour and 24 hours after exercise test) and 3 times post intervention (before, 1 hour and 24 hours after exercise test). Method of measurement: Specific kit.;Glutathione peroxidase (GPx) activity. Timepoint: 6 times: 3 times before the intervention (before, 1 hour and 24 hours after exercise test) and 3 times post intervention (before, 1 hour and 24 hours after exercise test). Method of measurement: Specific kit.;HSP-70 expressing mRNA. Timepoint: 6 times: 3 times before the intervention (before, 1 hour and 24 hours after exercise test) and 3 times post intervention (before, 1 hour and 24 hours after exercise test). Method of measurement: Specific kit.	—

Measure

Time frame

Total antioxidant capacity (TAC). Timepoint: 6 times: 3 times before the intervention (before, 1 hour and 24 hours after exercise test) and 3 times post intervention (before, 1 hour and 24 hours after exercise test). Method of measurement: Specific kit.;Malondialdehyde (MDA). Timepoint: 6 times: 3 times before the intervention (before, 1 hour and 24 hours after exercise test) and 3 times post intervention (before, 1 hour and 24 hours after exercise test). Method of measurement: Specific kit.;Super oxide dismutase (SOD) activity. Timepoint: 6 times: 3 times before the intervention (before, 1 hour and 24 hours after exercise test) and 3 times post intervention (before, 1 hour and 24 hours after exercise test). Method of measurement: Specific kit.;Glutathione peroxidase (GPx) activity. Timepoint: 6 times: 3 times before the intervention (before, 1 hour and 24 hours after exercise test) and 3 times post intervention (before, 1 hour and 24 hours after exercise test). Method of measurement: Specific kit.;HSP-70 expressing mRNA. Timepoint: 6 times: 3 times before the intervention (before, 1 hour and 24 hours after exercise test) and 3 times post intervention (before, 1 hour and 24 hours after exercise test). Method of measurement: Specific kit.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSevana Daneghian

Ahvaz Jundishapour University of Medical Sciences

sevana_d@yahoo.com; daneghian.s@ajums.ac.ir+98 61 3373 8330

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026