Relationship of Descurainia sophia L. with functional constipation in adults.
Conditions
Interventions
Intervention: A spoonful of dry seeds of Descurainia sophia L. and a spoonful of sugar in a cup of boiling water are mixed and taken at fasting once a day. If the properties of defecation do not sat
Treatment - Drugs
Sponsors
School of Traditional Medicine, Traditional Medicine and Materia Medica Research Center, Shahid Be
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age: 70-20 years at the time of screening; Ability to participate in the study and there is no obvious behavioral disorders, speech and language diaeres; No major abdominal surgery; Lack of self and family history of thyroid disease; Colon cancer screening in people over 50 years; Lack of warning signs (rectal bleeding and weight loss and anemia); No underlying disease affecting constipation (Parkinson, Multiple sclerosis, stroke, hypothyroidism, cancer); Lack of pregnancy or lactation; Speaking ins; Avoiding the use of antibiotics in the past 5 weeks; Not taking medications causing constipation; No addiction; Complete the consent form; Having normal routine tests, including complete blood count, fecal occult blood test, alkaline phosphatase and TSH test, liver enzymes and Cr; No previous sensitivities to herbal medicines; Absence of severe cardiovascular disease, especially functional class 3 & 4 of chronic heart failure; Lack of proven malignancy; Absence of liver disease (esophageal varices and bleeding, encephalopathy, ascites); Absence of symptomatic gallstone disease (in history); Absence of severe kidney disease (creatinine more than 3 mg / dl); Having the criteria for functional constipation ROMIII. Main exclusion criteria: Lack of durability of the above conditions; Unwillingness to continue participation in the study; Drug side effects or other threatening events.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of patients reaching three or more spontanouse complete bowel movement/week. Timepoint: At the begining, before the intervention and 4 weeks after, at the end of study. Method of measurement: By interviews with patients and asking them. | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of laxatives used. Timepoint: At the begining, before the intervention and 4 weeks after, at the end of study. Method of measurement: By interviews with the patients and asking them.;The score of a check list of Patient Assessment of Constipation Symptoms (PAC-SYM) items. Timepoint: At the begining, before the intervention and 4 weeks after, at the end of study. Method of measurement: By interviews with the patients and asking them.;The type of stool according to Bristol chart. Timepoint: At the begining, before the intervention and 4 weeks after, at the end of study. Method of measurement: By interviews with the patients and asking them. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Anahita Ghourchian
School of Traditional Medicine, Traditional Medicine and Materia Medica Research Center, Shahid Behe
Outcome results
None listed