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Evaluation of preventive effects of pentoxyfylline in contrast induced nephropathy

Evaluation of preventive effects of pentoxyfylline in contrast induced nephropathy in diabetic patients undergoing angioplasty

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201603038307N14
Enrollment
90
Registered
2017-07-09
Start date
2016-06-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes mellitus undergoing angioplasty. diabetes mellitus and ischemic heart disease

Interventions

intervention group will recieve 1200 mg pentoxyfylline three times divided dose with standard treatments control group will only recieve standard treatments.
Treatment - Drugs
intervention group will recieve 1200 mg pentoxyfylline three times divided dose with standard treatments control group will only recieve standard treatments

Sponsors

Vice chancellor for research, Tabriz University of Medical Sciences.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Ischemic heart diseases and diabetic patients; age 18-85; undergoing of angioplasty with stent insertion; filling of consent form. Exclusion Criteria: Elevation of CK-MB and cTnI before PCI; history of CABG during last three months; history of previous MI; renal dysfunction (creatinine above 2.5 mg/dl); unsuccessful PCI; acute MI; cardiogenic shock; dialysis; pregnancy; inability in filling and understanding of the consent form; unconsented patients; patients who want to discontinue the study at any time.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Cystatin c. Timepoint: 24 hours before and after. Method of measurement: elisa kit.

Secondary

MeasureTime frame
Creatinine. Timepoint: 24 hours before angioplasty and after. Method of measurement: elisa kit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Taher Entezari-maleki

tabriz university of medical science

tentezarimaleki@razi.tums.ac.ir+98 413344798

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026