Effect of curcumin in pre-procedural cardiac injury following angioplasty in ischemic heart diseases patients. Ischemic heart diseases
Conditions
Interventions
Intervention 1: Intervention: In curcumin group, all patients will be received totally 320mg oral curcumin before PCI plus the standard treatment. Intervention 2: Control: In the control group, patien
Treatment - Drugs
Intervention: In curcumin group, all patients will be received totally 320mg oral curcumin before PCI plus the standard treatment.
Sponsors
Vice chancellor for research, Tabriz University of Medical Sciences.
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Ischemic heart diseases patients; age 18-80; undergoing of angioplasty with stent insertion; filling of consent form. Exclusion Criteria: Elevation of CK-MB and cTnI before PCI; history of CABG during last three months; history of previous MI; renal dysfunction (creatinine above 2.5 mg/dl); unsuccessful PCI; acute MI; cardiogenic shock; dialysis; pregnancy; inability in filling and understanding of the consent form; unconsented patients; patients who want to discontinue the study at any time
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CK-MB level. Timepoint: Before, 8 and 24 hours after angioplasty. Method of measurement: ELISA kits. | — |
Secondary
| Measure | Time frame |
|---|---|
| CTnI level. Timepoint: Before, 8 and 24 hours after angioplasty. Method of measurement: ELISA kits. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Taher Entezari-Maleki
Tabriz University of Medical Sciences
Outcome results
None listed