Comparison of intravenous and intra-cuff Hydrocortisone on the severity of sore throat, cough and nausea after tracheal intubation during general anesthesia

Survey and Comparison of intravenous and intra-cuff Hydro cortisone on the severity of sore throat, cough and nausea after tracheal intubation during general anesthesia in distal limb fractures

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201603033064N3

Enrollment

135

Registered

2016-07-20

Start date

2016-01-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Distal limb fractures. Disorder of continuity of bone, unspecified

Interventions

Intervention 1: In the control group (group C), after intubation, endotracheal tube cuff will be filled with 5-10 ml of distilled water (routine). Intervention 2: In the intervention group (group B),

Treatment - Drugs

In the control group (group C), after intubation, endotracheal tube cuff will be filled with 5-10 ml of distilled water (routine)

In the intervention group (group B), 100 mg hydrocortisone diluted with 5-10 ml of distilled water, will be given intravenously.

In the intervention group (group A), after intubation, endotracheal tube cuff will be filled with 100 mg hydrocortisone diluted with 5-10 ml of distilled water

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Main inclusion criteria: ASA class 1 and 2 anesthesia; lack of drug addiction; aged between 60-18 years; no sore throat or hoarseness prior to surgery Main exclusion criteria: Acute upper respiratory infections; the history of steroids and narcotics use in a week before surgery

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Cough. Timepoint: 2, 6 and 24 hours after anesthesia. Method of measurement: Visual Analogue Scale (VAS).;Severety of sore throat. Timepoint: 2, 6 and 24 hours after anesthesia. Method of measurement: Visual Analogue Scale (VAS).;Nausea. Timepoint: 2, 6 and 24 hours after anesthesia. Method of measurement: Visual Analogue Scale (VAS).	—

Secondary

Measure	Time frame
. Timepoint: . Method of measurement: .	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hossein Bagheri

Shahroud University of Medical Sciences

bagheri@shmu.ac.ir+98 23 3239 5054

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026