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Treatment of wound with topical vitamin K

Double blind and randomized placebo- control clinical trial: Comparison of efficacy of topical vitamin K 1% and cream phenytoine 1% in skin wound healing

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016030226881N1
Enrollment
63
Registered
2016-05-17
Start date
2016-01-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin wound. Ulcer of skin NOS

Interventions

Intervention 1: In intervention group, patients treat with topical vitamin k cream 1% on skin wound. Patients evaluate in days 4, 7 and 14 for complication and response to treatment. Intervention 2: I
Treatment - Drugs
In intervention group, patients treat with topical vitamin k cream 1% on skin wound. Patients evaluate in days 4, 7 and 14 for complication and response to treatment.
In control group, patients treat with topical glycerin cream on skin wound. Patients evaluate in days 4, 7 and 14 for complication and response to treatment.
In standard group, patients treat with topical phenytoin cream 1% on skin wound. Patients evaluate in days 4, 7 and 14 for complication and response to treatment.

Sponsors

Ahwaz Jundishapur University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with skin; lack of sensitivity to vitamin k cream and phenytoin cream and glycerin; the last two months of non-use of other therapies; patients agreed to participate in the study. Exclusion criteria: drug reactions; other treatment methods; withdrawal patient cooperation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Wound size change. Timepoint: 4th, 7th and 14th days. Method of measurement: Zone measurement with special paper.

Secondary

MeasureTime frame
Dispigmentation; Infection; Erythema and Irritation. Timepoint: 4th, 7th and 14th days. Method of measurement: Observation and question.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Zahra Zeineli

Ahwaz Jundishapur University of Medical Sciences

zeineli_z@ajums.ac.ir+98 980112921837

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026