The Efficacy of Lippia Citriodora and placebo on sleep quality

Comparing the effectiveness of Lippia Citriodora and Placebo on sleep quality

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016030226875N1

Enrollment

100

Registered

2016-07-01

Start date

2016-07-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insomnia. Insomnia

Interventions

Intervention 1: For the intervention group 10 cc of lemon syrup 10%(In each 0ne cc of lemon syrup containing one tenth of aquenous extract of lippia citriodora) at the night ( one hour befor bedtime)

Treatment - Drugs

Placebo

For the intervention group 10 cc of lemon syrup 10%(In each 0ne cc of lemon syrup containing one tenth of aquenous extract of lippia citriodora) at the night ( one hour befor bedtime) for 4 weeks

For the placebo group, sugar syrup at a rate of 10 cc at the night (one hour befor bedtime) for 4 weeks

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: willingness to cooperate; older than eighteen years; diagnosis of insomnia based on diagnostic criteria of DSM-5; Score higher than five based on PSQI questionnaire(PSQI: Score> 5 ). Exclusion criteria: pregnancy and lactation; severe mental illness( such as: Severe depression; psychosis; severe anxiety disorders) ; severe physical illnesses( such as heart; liver; kidney; and respiratory disease; cancer;dementia); Having physical illness that directly or indirectly(Pain or medicine) caused Insomnia.; alcohol and Substance abuse;-taking medicine that affect on the sleep process of patient during the two weeks ago; Shift working patient; restless Leg Syndrome; occuring complications and improper take of drug during the study; history of allergy to Lemon verbena (lippia Citriodora).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Insomnia severity. Timepoint: In the beginning and after two and four weeks of the study. Method of measurement: ISI questionnaire.;Sleep quality. Timepoint: In the beginning and after two and four weeks of the study. Method of measurement: PSQI questionnaire.;Subjective sleep quality. Timepoint: In the beginning and after two and four weeks of the study. Method of measurement: PSQI questionnaire.;Habitual sleep efficiency. Timepoint: In the beginning and after two and four weeks of the study. Method of measurement: PSQI questionnaire.;Sleep latency. Timepoint: In the beginning and after two and four weeks of the study. Method of measurement: PSQI questionnaire.	—

Measure

Time frame

Insomnia severity. Timepoint: In the beginning and after two and four weeks of the study. Method of measurement: ISI questionnaire.;Sleep quality. Timepoint: In the beginning and after two and four weeks of the study. Method of measurement: PSQI questionnaire.;Subjective sleep quality. Timepoint: In the beginning and after two and four weeks of the study. Method of measurement: PSQI questionnaire.;Habitual sleep efficiency. Timepoint: In the beginning and after two and four weeks of the study. Method of measurement: PSQI questionnaire.;Sleep latency. Timepoint: In the beginning and after two and four weeks of the study. Method of measurement: PSQI questionnaire.

—

Secondary

Measure	Time frame
??Drug side effects. Timepoint: At the during of study. Method of measurement: By asking the patient.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarshid Afrasiabian

Faculty of Traditional Medicine, Shahid Sadoughei University of Medical Sciences, Ardakan, Yazd

farshid@ssu.ac.ir; farshidafrasiabian@gmail.com; farshidafra50@gmail.com+98 35 2723 8917

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026