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Effect of Tetracycline in the treatment of chronic periodontitis

Comparative Evaluation of Mucoadhesive Locally Delivery Tetracycline Gel and Tetracycline Gel in Treatment of Chronic Periodontitis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016030226872N1
Enrollment
75
Registered
2016-06-29
Start date
2016-05-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis. Chronic periodontitis

Interventions

Intervention 1: Control group:SRP with placebo. Intervention 2: Intervention group:SRP with Mucoadhesive Locally Delivery Tetracycline 5%. Intervention 3: Intervention group:SRP with Tetracyclin 5%.
Placebo
Treatment - Drugs
Intervention group:SRP with Mucoadhesive Locally Delivery Tetracycline 5%
Intervention group:SRP with Tetracyclin 5%

Sponsors

Ethics committee of Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patient free from systemic illness; patients who had note history of allergy to tetracycline; patiens having at least three sites with minimum 5 mm periodontal pocket; patient who had not taken antibiotic therapy and prophylaxy and periodontal therapy in the past 6 month Exlusion criteria: dissatisfaction and inability to comply with the follow-up visit requirments; history of systemic illness; received antibiotic treatment 2 weeks prior to study; pregnant and nursing patients

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Probing pocket depth. Timepoint: Baseline, two weeks, one and three months after the intervention. Method of measurement: Williams Periodontal Probe.;Clinical attachment loss. Timepoint: Baseline, two weeks, one and three months after the intervention. Method of measurement: Williams Periodontal Probe.;Plaque index. Timepoint: Baseline, two weeks, one and three months after the intervention. Method of measurement: plaque index Silness & Loe.;Gingival Index. Timepoint: Baseline, two weeks, one and three months after the intervention. Method of measurement: Observed.;Bleeding Index. Timepoint: Baseline, two weeks, one and three months after the intervention. Method of measurement: Observed\Bleeding Index Muhlemann.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarzie Jamali

Kermanshah Dentistry School

m.jamali174@gmail.com+98 83 3722 2400

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026