Comparing the efficacy of intravenous Caffeine versus intravenous Aminophylline in reduction of post-spinal anesthesia headache in cesarean sections

Comparing the efficacy of intravenous Caffeine versus intravenous Aminophylline in reduction of post-spinal anesthesia headache in cesarean sections in Amiralmomenin Hospital in 2013 and 2014

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016030126865N1

Enrollment

210

Registered

2016-05-14

Start date

2014-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-dural puncture headache. Spinal and epidural anaesthesia-induced headache during pregnancy

Interventions

Intervention 1: Intervention 1:Administration of intravenous Aminophylline 1.5 mg/kg in recovery room after cesarean. Intervention 2: Intervention 2:Administration of intravenous caffeine 30 mg plus 1

Prevention

Intervention 1:Administration of intravenous Aminophylline 1.5 mg/kg in recovery room after cesarean

Intervention 2:Administration of intravenous caffeine 30 mg plus 100cc normal saline in recovery room after cesarean.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion: consent to participate in the study; elective cesarean section; ASA (American Society of Anesthesiologists)=1; lack of sensivity to Caffeine and Aminophylline; No history of headache exclusive: The need for general anesthesia during surgery; opioide use during surgery

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Severity of post dural puncture headache. Timepoint: 4-24-48 hour after surgery. Method of measurement: VAS (visual Analog Scale).	—

Secondary

Measure	Time frame
Time of headache. Timepoint: 4-24-48 hour after surgery. Method of measurement: Patients According.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFereshteh Odar

Islamic Azad University Tehran Medical Science branch

Fereshteh.odar@yahoo.com+98 21 2200 6660

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026