Intranasal Dexmedetomidine and Remifentanil and hemodynamic changes after intubation in children

Comparison the effect of intranasal dexmedetomidine and remifentanil on reduction of hemodynamic changes after intubation in children ages 6 to 12 years old under general anesthesia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160301026866N7

Enrollment

105

Registered

2018-09-04

Start date

2018-09-23

Completion date

Unknown

Last updated

2018-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic and Respiratory complications after intubation.

Interventions

Intervention group 1: Two minutes before anesthesia induction received 4 µg / kg of Intranasal remifentanil .Intervention group 2: Two minutes before anesthesia induction, 2 µg / kg intranasal Dexmede

Eligibility

Sex/Gender

All

Age

6 Years to 12 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: all children ages 6 to 12 years of age with general anesthetics, ASAI and ASAII grades, and consent from the parents of the patient to participate in the study.

Exclusion criteria

Exclusion criteria: The criteria for not attending the study include children under 6 years of age and over 12 years of age, underlying illness (inherited and genetic diseases, metabolic diseases, etc.), and parents' disagreement for participation in the study

Design outcomes

Primary

Measure	Time frame
Hemodynamic change. Timepoint: One minute after the drug is given and one minute after the intubation. Method of measurement: Anesthetic monitoring device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Shafa

Esfahan University of Medical Sciences

shafa_amir@yahoo.com+98 31 3773 5509

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026