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Evaluation of fractional laser and topical antifungal effectiveness versus systemic antifungal to improve onychomycosis

Evaluation of fractional laser and topical antifungal effectiveness versus systemic antifungal in patients with onychomycosis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016022925539N6
Enrollment
54
Registered
2016-04-21
Start date
2015-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

onychomycosis. Tinea unguium

Interventions

Intervention 1: Intervention group 1 : Cases will be treated with fractional laser, 3 sessions with a month intervals between them and Terbinafine 1 % cream topically twice daily. Due to painful proce
Treatment - Devices
Treatment - Drugs
Intervention group 1 : Cases will be treated with fractional laser, 3 sessions with a month intervals between them and Terbinafine 1 % cream topically twice daily. Due to painful procedure, there is n
Control group : The control group will be treated with oral Terbinafine 250 mg tablet daily for 3 months.

Sponsors

Vice chancellor for research , Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Onychomycosis Infection ; lack of topical or oral drug allergy Exclusion criteria: Absence of follow up by patients and Lack of consent for treatment; Complications such as allergy to topical or oral agent

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Fungal nail infection. Timepoint: 0, 1 and 2 months during treatment . And 3 and 6 months after treatment. Method of measurement: The involvement of the nail plate with standard photography.

Secondary

MeasureTime frame
Response to treatment According to the patient. Timepoint: After completion of treatment. Method of measurement: The percentage and score of the patient to treatment (0 to 100%).;Satisfaction amount. Timepoint: After completion of treatment. Method of measurement: Comparison of reduction nail involvement by patient , before and after treatment According to schedule (score 0 to 10).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahba Azizi

Iran University Of Medical Sciences

Mahbaazizi@yahoo.com+98 21 6698

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026