Androgenetic alopecia. Androgenic alopecia
Conditions
Interventions
Intervention 1: Intervention: 20 drops of a minoxidil topical solution 5% on the affected areas twice daily plus 20-minute sessions of low level light laser therapy (LLLT) using a laser comb (LDU 8024
Treatment - Devices
Treatment - Drugs
Intervention: 20 drops of a minoxidil topical solution 5% on the affected areas twice daily plus 20-minute sessions of low level light laser therapy (LLLT) using a laser comb (LDU 8024PN/8024BN, Germa
Control: 20 drops of a minoxidil topical solution 5% (Pak Darou, Iran) on the affected areas twice daily.
Sponsors
Vice Chancellor for Research, Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
17 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: consent to participate; absence of other causes of hair loss; types 1-4 on Fitzpatrick scale; stages 3-6 on Norwood Hamilton Scale (for male patter baldness); stages 2-3 on the Ludwig Scale for hair loss in women; no history of finasteride, antiandrogens (e.g. cyproterone, spironolactone, ketoconazole, and flutamide), topical estrogen, progesterone, tamoxifen, anabolic steroids, drugs potentially associated with hypertrichosis (e.g. cyclosporine, diazoxide, phenytoin, oral glucocorticoids, lithium, and phenothiazine during the three-month period before the study. Exclusion criteria: using the above-mentioned medicines during the study; lack of adherence to treatment protocol; hair transplant; any medical conditions leading to hair loss (e.g. HIV/AIDS, connective tissue disease, and inflammatory bowel disease); development of endocrinopathies such as PCO, ovarian and adrenal gland tumors, and hypothyroidism.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hair density. Timepoint: Before the intervention, 3, 6, 9, and 12 months after the intervention. Method of measurement: Phototrichogram.;Hair shaft diameter. Timepoint: Before the intervention, 3, 6, 9, and 12 months after the intervention. Method of measurement: Phototrichogram.;Patient satisfaction. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Questionnaire.;Hair regrowth based on patient's opinion. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Visual analog scale.;Hair regrowth based on physician's opinion. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Digital image and observation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Headache. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Asking patients.;Erythema. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Asking patients.;Itching. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Asking patients.;Hypopigmentation. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Observation and asking patients.;Hyperpigmentation. Timepoint: 3, 6, 9, and 12 months after the intervention. Method of measurement: Observation and asking patients. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamane Mozafarpoor
Isfahan University of Medical Sciences
Outcome results
None listed