Effects of oral clonidine on blood pressure and postoperative shivering

Effects of premeditation clonidine on hemodynamic response to endotracheal intubation and carbon dioxide pneumoperitoneum (insufflation)and scale of postoperative shivering in patients undergoing laparoscopic cholecystectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016022716612N4

Enrollment

Registered

2016-06-07

Start date

2015-10-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cholecystectomy laparoscop. cholelitihiasis,cholecystitis,other deases of gallbladder

Interventions

Intervention 1: Group intervention : tab oral clonidine 150 microgram. Intervention 2: Group control : oral vitamin C 100 miligram.

Prevention

Placebo

Group intervention : tab oral clonidine 150 microgram

Group control : oral vitamin C 100 miligram

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : patients undergoing laparoscopic cholecystectomy ; the age range 18_70 years ; on both the male and female Exclusion criteria:having hypertension ; hypotension; morbid obesity; sever hepatitis; endocrine diseases; kidney diseases; heart diseases

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Change of blood pressure and heart rate. Timepoint: Before starting surgery and before Laryngoscopy and immediately after tracheal intubation and every 1_5 minutes before blowing carbon dioxide and 5,15 and 30 minutes after the blowing of carbon dioxide gas. Method of measurement: mm hg_counting heart beats.	—

Secondary

Measure	Time frame
Check in scale of shivering. Timepoint: check in scale of postoperative shivering based on observation muscle movement recovery and scored. Method of measurement: score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Masaud Entezari

Ardabil University of Medical Sciences

M.entezari@arums.ac.ir+98 45 3325 1688

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026