Condition 1: Nasal polyposis. Condition 2: Nasal polyp. Polyp of nasal cavity
Conditions
Interventions
Intervention 1: 1 intervention groups: ]n this group of patients recieve Placebo with 50 cc of water, one hour before surgery .During surgery patient's vital signs, including blood pressure measuremen
Treatment - Drugs
1 intervention groups: ]n this group of patients recieve Placebo with 50 cc of water, one hour before surgery .During surgery patient's vital signs, including blood pressure measurement, ECG, heart ra
2intervention groups: ]n this group of patients recieve 4mg Tizanidin with 50 cc of water, one hour before surgery .During surgery patient's vital signs, including blood pressure measurement, ECG, hea
Sponsors
Vice Chancellor for research of Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
16 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age more than 16 years undergoing endoscopic sinus surgery • ASA class I and II Exclusion criteria : • high blood pressure (severe) • liver or kidney disease •coagulopathy • Diabetes • Abnormal blood sugar on the morning of the day of surgery • severe hypotension during surgery that requires intravenous administration of large volumes • Lack of consent to participate in the study have. Aspirin or any anticoagulants drugs. hemoglobin under 10.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding. Timepoint: after 1 hour. Method of measurement: check list.;Severity of nasal sinus bleeding. Timepoint: before induction, after induction, 5, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80 minutes. Method of measurement: heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure. | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgeon consent. Timepoint: based on Likert scale. Method of measurement: It will be measured based on a verbal descriptive scale which is related with a visual bleeding score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSaleheh Asghari
Mashhad University of Medical Sciences
Outcome results
None listed