The effect of a new bone material in the treatment of bony defects caused by periodontal disease: A randomized clinical trial

Comparative effect of Nanobone and Bio-Oss on bone regeneration in periodontal defects: A randomized clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016022624622N2

Enrollment

100

Registered

2016-04-25

Start date

2016-03-31

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis. Chronic Periodontits

Interventions

Intervention 1: Treatment using Bio-Oss in the control group. Surgery is done using a full thickness flap with an extension of one tooth at each side of the defect. After flap reflection a complete de

Treatment using Bio-Oss in the control group. Surgery is done using a full thickness flap with an extension of one tooth at each side of the defect. After flap reflection a complete debridement of the

Treatment using Nanobone in the test group. Surgery is done using a full thickness with extension of one tooth at each side of the defect. After flap reflection a complete debridement of the defect wo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with at least one vertical defect assessed by clinical and radiographic evaluation; Patients with no systemic disease

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Depth of the defect. Timepoint: At the first surgery day. Method of measurement: Using a periodontal probe.;Keratinized tissue. Timepoint: At the first surgery day. Method of measurement: Using a periodontal probe.;Bleeding on probing. Timepoint: At the first surgery day. Method of measurement: Using a periodontal probe.;Clinical attachment level. Timepoint: At the first surgery day. Method of measurement: Using a periodontal probe.;Gingival recession. Timepoint: At the first surgery day. Method of measurement: Using a periodontal probe.;Plaque index. Timepoint: At the first surgery day. Method of measurement: Disclosing agents.;Width of the defect. Timepoint: At the first surgery day. Method of measurement: Using a periodontal probe.;Pocket depth. Timepoint: At the first surgery day. Method of measurement: Using a periodontal probe.	—

Measure

Time frame

Depth of the defect. Timepoint: At the first surgery day. Method of measurement: Using a periodontal probe.;Keratinized tissue. Timepoint: At the first surgery day. Method of measurement: Using a periodontal probe.;Bleeding on probing. Timepoint: At the first surgery day. Method of measurement: Using a periodontal probe.;Clinical attachment level. Timepoint: At the first surgery day. Method of measurement: Using a periodontal probe.;Gingival recession. Timepoint: At the first surgery day. Method of measurement: Using a periodontal probe.;Plaque index. Timepoint: At the first surgery day. Method of measurement: Disclosing agents.;Width of the defect. Timepoint: At the first surgery day. Method of measurement: Using a periodontal probe.;Pocket depth. Timepoint: At the first surgery day. Method of measurement: Using a periodontal probe.

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Secondary

Measure	Time frame
Bleeding on probing. Timepoint: 6 months after first surgery. Method of measurement: Using a periodontal probe.;Gingival recession. Timepoint: 6 months after first surgery. Method of measurement: Using a periodontal probe.;Clinical attachment level. Timepoint: 6 months after first surgery. Method of measurement: Using a periodontal probe.;Depth of the defect. Timepoint: 6 months after first surgery. Method of measurement: Using a periodontal probe.;Pocket depth. Timepoint: 6 months after first surgery. Method of measurement: Using a periodontal probe.;Keratinized tissue. Timepoint: 6 months after first surgery. Method of measurement: Using a periodontal probe.;Width of the defect. Timepoint: 6 months after first surgery. Method of measurement: Using a periodontal probe.;Plaque index. Timepoint: 6 months after first surgery. Method of measurement: using disclosing agent.	—

Measure

Time frame

Bleeding on probing. Timepoint: 6 months after first surgery. Method of measurement: Using a periodontal probe.;Gingival recession. Timepoint: 6 months after first surgery. Method of measurement: Using a periodontal probe.;Clinical attachment level. Timepoint: 6 months after first surgery. Method of measurement: Using a periodontal probe.;Depth of the defect. Timepoint: 6 months after first surgery. Method of measurement: Using a periodontal probe.;Pocket depth. Timepoint: 6 months after first surgery. Method of measurement: Using a periodontal probe.;Keratinized tissue. Timepoint: 6 months after first surgery. Method of measurement: Using a periodontal probe.;Width of the defect. Timepoint: 6 months after first surgery. Method of measurement: Using a periodontal probe.;Plaque index. Timepoint: 6 months after first surgery. Method of measurement: using disclosing agent.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactVahid Raziani

Hamedan University of Medical Sciences

vahidraziani@gmail.com+98 81 3824 7464

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026