Effect of naloxone on ileus after caesarean section by spinal anesthesia

Effect of ultra low dose naloxone on post-operative ileus after caesarean section by spinal anesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016022426357N2

Enrollment

Registered

2016-08-24

Start date

2014-12-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ileus. Ileus, unspecified

Interventions

Intervention 1: Group A) intervention (combination of morphine and naloxone pump PCA contains 30 mg dose of 0.25µg / kg / hr manufacturing pharmaceutical company producing the drug and the rest of the

Treatment - Drugs

Group A) intervention (combination of morphine and naloxone pump PCA contains 30 mg dose of 0.25µg / kg / hr manufacturing pharmaceutical company producing the drug and the rest of the volume of 100 c

group) B (control: internal composition contains 30 mg of morphine PCA pump and the rest of the volume of 100 cc (total volume pump PCA) has become saline. profile settings PCA pump would then be: the

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria (inclusion criteria): The willingness of patients to participate in the study and informed consent; first elective cesarean section under spinal anesthesia; Age> 18 years; ASA Class ? Exclusion criteria (exclusion criteria): Any contraindication to spinal anesthesia; Taking prokinatic; Irritable Bowel Syndrome; drug addiction;

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Ileus. Timepoint: as soo. Method of measurement: Upon arrival to the recovery room, 30 minutes, 60 minutes, 90 minutes, 120 minutes, 6, 12 and 24 hours after operation.	—

Secondary

Measure	Time frame
Pain. Timepoint: Upon arrival to the recovery room, 30 minutes, 60 minutes, 90 minutes, 120 minutes, 6, 12 and 24 hours. Method of measurement: VAS.;VOMITING. Timepoint: Upon arrival to the recovery room, 30 minutes, 60 minutes, 90 minutes, 120 minutes, 6, 12 and 24 hours. Method of measurement: VAS.;NAUSEA. Timepoint: Upon arrival to the recovery room, 30 minutes, 60 minutes, 90 minutes, 120 minutes, 6, 12 and 24 hours. Method of measurement: VAS.;Itching. Timepoint: Upon arrival to the recovery room, 30 minutes, 60 minutes, 90 minutes, 120 minutes, 6, 12 and 24 hours after surgery. Method of measurement: VAS.	—

Measure

Time frame

Pain. Timepoint: Upon arrival to the recovery room, 30 minutes, 60 minutes, 90 minutes, 120 minutes, 6, 12 and 24 hours. Method of measurement: VAS.;VOMITING. Timepoint: Upon arrival to the recovery room, 30 minutes, 60 minutes, 90 minutes, 120 minutes, 6, 12 and 24 hours. Method of measurement: VAS.;NAUSEA. Timepoint: Upon arrival to the recovery room, 30 minutes, 60 minutes, 90 minutes, 120 minutes, 6, 12 and 24 hours. Method of measurement: VAS.;Itching. Timepoint: Upon arrival to the recovery room, 30 minutes, 60 minutes, 90 minutes, 120 minutes, 6, 12 and 24 hours after surgery. Method of measurement: VAS.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtefeh Hadian

Mazandaran University of Medical Science

md.hadian@gmail.com+98 11 3226 1700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026