Infertility. Female infertility
Conditions
Interventions
Intervention 1: In Agonist -Antagonist protocol in second day of cycle agonist GNRH (DECAPEPTYL0.1MG)used SC for 3 days and then gonadotropin (Gonal-f ) administered. After 6 days vaginal sonography
Treatment - Drugs
In Agonist -Antagonist protocol in second day of cycle agonist GNRH (DECAPEPTYL0.1MG)used SC for 3 days and then gonadotropin (Gonal-f ) administered. After 6 days vaginal sonography done frequently
In Long protocol in second or third day of cycle OCP started for 21 days. In Mid-luteal phase agonist GNRH (SUPERFACT) administered for 7 days and menstruation started and In second or third day of
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Inclusion criteria: normal responder infertile patients included (It means age less than 40 and normal ovarian reserve( 6AMH>1); also patients had good response to previous ovarian stimulation: BMI more than 30 . Exclusion criteria: low responder patients; high responder patients; using donated oocyte and donated egg; single ovary; endometriosis; if patient's husband need to use TESE and PESA.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of oocyte metaphase 2. Timepoint: After ovarian puncture. Method of measurement: Microscope- by counting oocyte. | — |
Secondary
| Measure | Time frame |
|---|---|
| Age. Timepoint: Chronological age. Method of measurement: Birth Certificate - year.;Time of infertility. Timepoint: At first. Method of measurement: Interviews with patient - year.;Type of infertility. Timepoint: At first. Method of measurement: Interviews with patient - Infertility divided in two groups: primary (no pregnancy history) and secondary.;Chemical pregnancy. Timepoint: Two weeks after transfer. Method of measurement: Blood test - bhcg titration.;Clinical pregnancy. Timepoint: Four weeks after transfer. Method of measurement: Vaginal sonography - View gestational sac and fetal heart rate.;The number of matured follicle. Timepoint: Before puncture. Method of measurement: Vaginal sonography - The number of matured oocyte with size of18mm or more.;The number of antral follicle. Timepoint: At first. Method of measurement: Vaginal sonography - The number of antral follicle with size of 2-9 mm in follicular phase.;The number of punctured oocyte. Timepoint: After puncture. Method of measurement: Microscope - The number of punctured oocyte.;The number of fetus. Timepoint: After puncture. Method of measurement: Microscope-The number of fetuses after injection.;The number of transferred fetus. Timepoint: In the time of transfer. Method of measurement: Microscope - The number of fetuses transfer in uterine.;The days stimulation. Timepoint: At first of cycle. Method of measurement: Documents - The number of days that using gonadotropin.;Endometrial thickness. Timepoint: Before transfer. Method of measurement: Vaginal sonography - mm.;BMI. Timepoint: At first. Method of measurement: Examination of patient - Dividing weight in kg by the square of one's height in cm.;The number of drug used. Timepoint: In the end of treatment. Method of measurement: Documents - The number of drugs using for ovarian stimulation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Fateme Fakhar Moghadam
Shariati Hospital, Tehran University of Medical Sciences
Outcome results
None listed