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The effect of treatment of constipation on improving migraine

The effect of treatment of constipation by lactoluse on the migraine improving in patients with migraine headache

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016022226667N3
Enrollment
60
Registered
2016-04-03
Start date
2016-04-30
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine. Migraine

Interventions

Intervention 1: In the intervention group, as long as patients treated constipation, in addition to the drug, given daily for 15 to 30 cc lactulose syrup. Intervention 2: The control group, in additio
That is poured into the same bottles.
Treatment - Drugs
In the intervention group, as long as patients treated constipation, in addition to the drug, given daily for 15 to 30 cc lactulose syrup.
The control group, in addition to medication, placebo given daily 20 cc

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Having a history of migraines for 6 months; Headache frequency by at least three times a month; Age 15 to 50 years, Avoiding the use of prophylactic medication. Exclusion criteria: unwillingness to continue the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Headache. Timepoint: Before, one and two moanth after intervention. Method of measurement: Questionnaire of visual analoge scale.

Secondary

MeasureTime frame
Disability. Timepoint: Before, one and two mounth after intervention. Method of measurement: Questionnaire of MIDAS.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Jadidi

Arak University of Medical Sciences

jadidi@arakmu.ac.ir; jadidi.ali83gmail.com+98 86 3417 3508

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026