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Effectiveness of pregabalin on chronic nonbacterial prostatitis

Effectiveness of pregabalin as an adjuvant therapy for chronic nonbacterial prostatitis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016022225507N2
Enrollment
288
Registered
2016-03-01
Start date
2016-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic nonbacterial prostatitis. Other inflammatory diseases of prostate

Interventions

Intervention 1: Control group: Patients with chronic nonbacterial prostatitis use of Terazosin tablets (2 mg) and placebo capsules (50 mg) on a daily basis for the first week, followed by the daily us
Treatment - Drugs
Control group: Patients with chronic nonbacterial prostatitis use of Terazosin tablets (2 mg) and placebo capsules (50 mg) on a daily basis for the first week, followed by the daily use of 100 mg plac
Intervention group: Patients with chronic nonbacterial prostatitis use of terazosin tablets (2 mg) and pregabalin capsules (50 mg) on a daily basis for the first week, followed by the daily use of 100

Sponsors

Vice Chancellor for Research of Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 139 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1) Age over 18 years; 2) no prior history of other urinary system disorders such as urinary tract stones, neurogenic bladder, and urinary infections; 3) no history of major underlying diseases such as cirrhosis, renal failure, diabetes, or hypertension; 4) normal levels of urine, fasting blood sugar (FBS), and creatinine; 5) normal results on the first neurological examination of the perineal area, lower limbs, lower limb reflexes, and bulbocavernosus reflex; 6) no use of other medicines; 7) no signs of psychological disorders; 8) confirmed diagnosis of chronic prostatitis; 9) non-sensitivity to anti-epileptic drugs, pregabalin, thiazolidinediones, or other anti-diabetic agents. Exclusion criteria: 1) Unwillingness to continue the study, and 2) major side-effects due to the use of medications.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Rang of pain. Timepoint: 6 weeks after therapy. Method of measurement: NIH-CPSI scoring system, Scoring from 0 to 21.

Secondary

MeasureTime frame
Urinary symptoms. Timepoint: 6 weeks after therapy. Method of measurement: NIH-CPSI scoring system, Scoring from 0 to 10.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Sirous

Arak University of Medical Sciences

m-jiriaie@mscstu.scu.ac.ir+98 86 3313 6058

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026