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Investigating the effect of sensory training on pain and function in people with anterior knee pain

Investigating the effect of tactile acuity training on pain, function, tactile acuity, and descending pain pathway activity in patients with chronic patellofemoral pain accompanied by central sensitization: A randomized clinical trial study

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160221026674N6
Enrollment
36
Registered
2025-06-22
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patellofemoral pain. Patellofemoral disorders

Interventions

Intervention 1: Intervention group: Tactile acuity training and standard physiotherapy exercises. Intervention 2: Control group: Standard physiotherapy exercises.

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Pain in the back or around the patella Increased pain in the back or around the patella with activities such as squatting, climbing stairs, sitting for long periods of time, or other functional activities that place stress on the patellofemoral joint in a flexed position Positive Grind test Complaints of pain in the front of the knee for more than 6 months Pain 3 to 7 on the NRS Minimum score of 40 on the Central sensitization Questionnaire Individuals between 18 and 40 years old Reported pain on palpation of the medial and lateral surfaces of the patella Gradual onset of symptoms without prior history of trauma or injury Positive Clark's clinical test Kujala score level between 50 and 80

Exclusion criteria

Exclusion criteria: Other knee joint pathologies Tenderness to touch in the soft tissue around the knee Any joint damage and pain Visceral pain Disorders in the vertebral column Previous lower limb surgery Taking nonsteroidal anti-inflammatory drugs in the last two weeks Any causes of neuropathy and disorders in the sensory-motor system Neurological diseases Rheumatological and collagen vascular diseases Difference in length of lower limbs History of cancer and chemotherapy Substance and alcohol abuse Pregnancy

Design outcomes

Primary

MeasureTime frame
Graphesthesia. Timepoint: Before intervention; Immediately after intervention; 2 weeks after intervention. Method of measurement: Identifying the correct number of letters and numbers drawn on the skin.;Two point discrimination. Timepoint: Before intervention; Immediately after intervention; 2 weeks after intervention. Method of measurement: Sliding caliper.;Point-to-point sensation. Timepoint: Before intervention; Immediately after intervention; 2 weeks after intervention. Method of measurement: Monofilament.;Pain. Timepoint: Before intervention; Immediately after intervention; 2 weeks after intervention. Method of measurement: NRS.

Secondary

MeasureTime frame
Function. Timepoint: Before intervention; Immediately after intervention; 2 weeks after intervention. Method of measurement: Kujala questionnaire.;Descending pain inhibitory pathway activity. Timepoint: Before intervention; Immediately after intervention; 2 weeks after intervention. Method of measurement: Conditioned pain modulation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarzieh Mohamadi

Shiraz University of Medical Sciences

mohamadm@sums.ac.ir+98 71 3212 2600

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026