Evaluation effect of Pramipexole in patients with migraine and restless legs syndrome at the same time

Evaluation effect of Propranolol and Pramipexole compared with Propranolol and placebo on treatment of Migrain headache in patients with Migraine and restless legs syndrome at the same time in patient referred to neurology clinic of Ahwaz Golestan hospital

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016022026166N1

Enrollment

Registered

2016-08-31

Start date

2015-08-15

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migrain, restless legs syndrome. Migraine, Other extrapyramidal and movement disorders

Interventions

Intervention 1: First group will treat with Propranolol 20 mg twice a day and placebo two hour before sleep time for three months . Intervention 2: Second group will treat with Propranolol 20 mg twice

Treatment - Drugs

First group will treat with Propranolol 20 mg twice a day and placebo two hour before sleep time for three months .

Second group will treat with Propranolol 20 mg twice a day and Pramipexol 0.7 mg two hours before sleep time for three months .

Eligibility

Sex/Gender

All

Age

15 Years to 50 Years

Inclusion criteria

Inclusion criteria: Main inclusion criteria: No pregnant weman? No menopause weman ?No history of Alcohol or substance addiction ?No history of cardiac block or bradycardia?No history of second cause for restless legs syndrome Main exclusion criteria: Patient who stop continuing the study in each reason; Patient who will be menopause or pregnant

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Severity of Miigrain. Timepoint: Start and after 3 months. Method of measurement: Midas questionary.;Severity of restless leg syndrome. Timepoint: Start and after 3 months. Method of measurement: IRLLG questionary.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarzaneh Karimian

Ahwaz jundishapour university of medical science and health services

karimian.f@ajums.ac.ir+98 61 3374 3011

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026