Comparing the effect of methylphenidate and modafinil in the reduction of crystal withdrawal symptoms and craving

Comparing the effect of methylphenidate and modafinil in the reduction of methamphetamine withdrawal symptoms and craving

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016022025160N2

Enrollment

Registered

2016-05-05

Start date

2016-04-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Methamphetamine Dependency. Mental and behavioural disorders due to use of other stimulants, including caffeine

Interventions

Intervention 1: One group will receive methylphenidate for two weeks. Intervention 2: The other group will receive modafinil for two weeks.

Treatment - Drugs

One group will receive methylphenidate for two weeks

The other group will receive modafinil for two weeks

Eligibility

Sex/Gender

Male

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients' age should be between 18 to 50 years; Patients should fill the informed consent form; Methamphetamine is the main substance of abuse. Exclusion criteria: Patients unwilling to participate at beginning or during the study; Methamphetamine is not the main substance of abuse.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Craving. Timepoint: daily for 2 weeks. Method of measurement: questionnaire and interview.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJamshid Ahmadi M.D.

Shiraz University of Medical Sciences

jamshid_ahmadi@yahoo.comajmadij@sums.ac.ir+98 71 3646 1511

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026