Effect of gastrointestinal infection eradication on iron stores

Effect of helicobacter pylori eradication on iron stores in patients with dyspepsia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016021626593N1

Enrollment

108

Registered

2016-10-26

Start date

2016-05-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Helicobacter Pylori Infection. Condition 2: Iron Deficiency. Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere Iron deficiency anemia, unspecified

Interventions

Intervention 1: Intervention Group : 1- First Group : H.pylori eradication for 2 weeks and simultaneously use of iron complement for 8 weeks. 2- Second Group : H.pylori eradication for 2 weeks an

Treatment - Drugs

Intervention Group : 1- First Group : H.pylori eradication for 2 weeks and simultaneously use of iron complement for 8 weeks. 2- Second Group : H.pylori eradication for 2 weeks and when eradica

Control Group : H.Pylori eradication alone for 2 weeks. Drugs for eradication are : furazolidone 200mg/BD, omeprazole 20mg/BD, bismut 240mg/BD, Amoxicillin 1gr/BD.

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients with dyspepsia symptoms who their H pylori infection was proven by endoscopy and biopsy; ferritin serum level less than 40 ng /ml; negative CRP test. Exclusion criteria: History of treatment of helicobacter pylori during last 6 months; history of iron supplement intake among last 6 months; known underlying diseases associated with iron deficiency; lack of informed consent.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Hemoglubin. Timepoint: Before Intervention. Method of measurement: Sysmex K21.;CRP. Timepoint: Before Intervention. Method of measurement: Latex Aglutination.;Ferritin. Timepoint: Before and After Intervention. Method of measurement: Eliza Method.	—

Secondary

Measure	Time frame
Ferritin. Timepoint: After Intervention. Method of measurement: Eliza Method.;Helicobacter Pylori Fecal Antigen. Timepoint: After Intervention. Method of measurement: Stool Examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactfarhad yarmohammadi

Zahedan University of Medical Sciences

frdflower@zaums.ac.ir+98 54 3348 6260

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026