Effect of Atracurium ,Minidose of Succinylcholine and Placebo in Reduction of Succinylcholine Side Effects

A Clinical Trial Comparing of minidose of Succinylcholine, Atracurium and placebo in the prevention of Succinylcholine Consumption

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016021526566N1

Enrollment

Registered

2016-05-27

Start date

2015-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Succinylcholine Adverse Effects. Skeletal Muscle Relaxants [Neuromuscular blocking agents]

Interventions

Intervention 1: Placebo First Group: Normal saline, IV injection, Before induction of Anesthesia. Intervention 2: Atracurium Third Group: 0.03 mg/kg, IV injection, Before induction of Anesthesia. Int

Placebo

Treatment - Drugs

Placebo First Group: Normal saline, IV injection, Before induction of Anesthesia

Atracurium Third Group: 0.03 mg/kg, IV injection, Before induction of Anesthesia

Succinylcholine Second Group: 5 mg, IV injection, Before induction of Anesthesia

Eligibility

Sex/Gender

All

Age

76 Years to 44 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:ASA Iand II,Age between 18-50 years old.Exclusion criteria:Patients with severe trauma in the last 24-48 hours,Burns,Muscular dystrophy,Malignant hyperthermia, Patients that ICP and IOP are harmful for them.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Potassium level after intravenous injection of succinylcholine drug. Timepoint: Before surgery, 8 hours after surgery, 16 hours after surgery. Method of measurement: Concentration in blood mEq/l.;Pain level after intravenous injection of succinylcholine drug. Timepoint: Day after surgery. Method of measurement: Fill questionnaire and Asking patient aboat pain and Visual Scale.;Fasciculation level after intravenous injection of succinylcholine drug. Timepoint: After injection of drug. Method of measurement: Fill questionnaire and Visual Scale.;Potassium level after Intravenous injection of atracurium. Timepoint: Before surgery?8hours after surgery?16hours after surgery. Method of measurement: Concentration in blood mEq/l.;Pain level after intravenous injection of atracurium drug. Timepoint: Day after surgery. Method of measurement: Fill questionnaire and Asking patient about pain and visual scale.;Fasciculation level after intravenous injection of atracurium drug. Timepoint: After injection of drug. Method of measurement: Fill questionnaire and visual scale.	—

Measure

Time frame

Potassium level after intravenous injection of succinylcholine drug. Timepoint: Before surgery, 8 hours after surgery, 16 hours after surgery. Method of measurement: Concentration in blood mEq/l.;Pain level after intravenous injection of succinylcholine drug. Timepoint: Day after surgery. Method of measurement: Fill questionnaire and Asking patient aboat pain and Visual Scale.;Fasciculation level after intravenous injection of succinylcholine drug. Timepoint: After injection of drug. Method of measurement: Fill questionnaire and Visual Scale.;Potassium level after Intravenous injection of atracurium. Timepoint: Before surgery?8hours after surgery?16hours after surgery. Method of measurement: Concentration in blood mEq/l.;Pain level after intravenous injection of atracurium drug. Timepoint: Day after surgery. Method of measurement: Fill questionnaire and Asking patient about pain and visual scale.;Fasciculation level after intravenous injection of atracurium drug. Timepoint: After injection of drug. Method of measurement: Fill questionnaire and visual scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hamidreza Bahmani

Shiraz University of Medical Sciences

Pencillin2002@yahoo.com+98 71 3230 5410

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026