resistant cases of cutaneous leishmaniasis. Cutaneous leishmaniasis
Conditions
Interventions
Intervention group: Patients who have had a complete treatment period with intralesional glucantime injections and have resistance to treatment (no clinical improvement of lesions after 12 sessions of
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age more than 18 years; maximum lesion number is 4; duration of illness is less than one year; lesion type is dry Leishmaniasis (Clinical manifestation of urban leishmaniasis); There are no sings of lymphangitis and sporotrichoid; No more than 2 months has passed from the incidence of the lesion until wound formation; there is no widespread wound and secretion.
Exclusion criteria
Exclusion criteria: having other atypical forms such as lupoid-sporotrichoid-erysipeloid-zoster forms and....; patients who have had a heart attack within the last month; patients with unstable angina; patients with less than 100 spontaneous bacterial peritonitis (SBP) and consuming medications such as Azoles and Sodium Vauproat, and Macrolide and Fluoxetine due to the prohibition of Nimodipine use in these people; incidence of drug complications during treatment such as Phlebitis, hypotension, headache, severe nausea and vomiting; pregnancy; breastfeeding; the lesion is preferably not on the face.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in size and value of induration. Timepoint: Patients are evaluated every week until the end of treatment, one and a half months and three months after the end of the treatment. Method of measurement: Using caliper and measuring the diameter of lesion. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMarzieh Pishgouy
Mashhad University of Medical Sciences
Outcome results
None listed