Skip to content

The effect of gel containing Prunella vulgaris extract on labial herpes

The comparison between gel containing Prunella vulgaris extract and Acyclovir on treatment of labial herpes in patients with recurrent herpes labialis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016021412438N16
Enrollment
80
Registered
2016-03-03
Start date
2016-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

recurrent herpes labialis. Herpesviral vesicular dermatitis

Interventions

Intervention 1: intervention: topical herbal gel, 6 times a day (every 3 hours) for a week. Intervention 2: control: topical acyclovir, 6 times a day (every 3 hours) for a week.
Treatment - Drugs
intervention: topical herbal gel, 6 times a day (every 3 hours) for a week
control: topical acyclovir, 6 times a day (every 3 hours) for a week

Sponsors

Barij Research Center of Medicinal Herbs
Lead Sponsor
Vice chancellor for research of Kashan University of Medical Science
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion: People 18 to 70 years old with recurrent herpes labialis that Less than 12 hours have passed vesicate. Exclusion criteria: Pregnancy and lactatin; use the antiviral drug in the past two weeks; have a history of immunotherapy in the last year; stimulating the immune system in the last month; Other mucocutaneous disorders; history of RAS ;history of allergy to the plant used in the study of allergic reaction during the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Clinical symptoms of blisters. Timepoint: Baseline and End-of-trial. Method of measurement: Observation.;Burning. Timepoint: At days 0, 2, 4, 7. Method of measurement: VAS.;Iitching. Timepoint: At days 0, 2, 4, 7. Method of measurement: VAS.;Soreness. Timepoint: At days 0, 2, 4, 7. Method of measurement: VAS.;Tingling. Timepoint: At days 0,2,4,7. Method of measurement: VAS.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.M.Taghizadeh

Kashan University of Medical Sciences

mohsenta44@yahoo.com+98 31 5554 0021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026