Condition 1: Hypertension. Condition 2: Hyperglyceridaemia. Condition 3: Prediabetic. Condition 4: low HDL-C. Secondary hypertension, unspecified Pure hyperglyceridaemia Abnormal glucose tolerance test High-density lipoprotein deficiency
Conditions
Interventions
Intervention 1: for intervention group:
Curcumin Dietary Supplement, 40 mg soft gel, twice/ day by oral, for 3 months. Intervention 2: for intervention and control groups:
training low calorie- low gl
Treatment - Drugs
Lifestyle
Placebo
for intervention group:
Curcumin Dietary Supplement, 40 mg soft gel, twice/ day by oral, for 3 months
for intervention and control groups:
training low calorie- low glycemic index diet. for all participants, this training will be taught in baseline and in the end of 6th week.
for control group:
Standardized Placebo, quite similar to Curcumin soft gels, twice/ day, for 3 months by oral
Sponsors
Vice – Chancellery of Research & Technology Affairs of Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Age
24 Years to 65 Years
Inclusion criteria
Inclusion criteria: The main including criteria: Filling the consent form of the present project in the beginning of study; lack of any kinds of chronic diseases such as diabetes, renal diseases, tuberculosis, liver diseases and/or the history of cardiac surgery; possessing at least 3 items of all the 5 indexes of metabolic syndrome (based on the definition by NCEP ATP III) (in case of insulin resistance, patients must have fasting blood glucose less than 126 mg/dL, otherwise these patients diagnosed as diabetic patients and must have exclude from the study); lack of taking medicine to control blood glucose, blood lipid and hypertension; the age range between 25 to 65 year; lack of injecting insulin so as to blood glucose control. The main exclusion criteria: Lack of regular taking the given supplements; lack of following the given diet which evaluated by the analysis of 3 days recall questionnaire by using Nutritionist- 4 software; starting taking medicine or supplements that may be affect the results of test of investigated factors or oral contraceptives, estrogen, progesterone and corticosteroids; pregnancy; taking/receiving insulin or tablet to control the blood glucose; losing any of inclusion criteria during the time of conducting the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma Glucose. Timepoint: base line and aftar 3 months of begin. Method of measurement: in term of mg/ dL by biochemical kits.;Blood pressure. Timepoint: base line, at the end of 6th week and aftar 3 months of begin. Method of measurement: in term of mm Hg by Mercury barometers.;Plasma HDL-C. Timepoint: base line and aftar 3 months of begin. Method of measurement: in term of mg/ dL by biochemical kits.;Plasma TG. Timepoint: base line and aftar 3 months of begin. Method of measurement: in term of mg/ dL by biochemical kits.;Waist Circumference. Timepoint: base line, at the end of 6th week and aftar 3 months of begin. Method of measurement: in term of centimeter by Tape measure. | — |
Secondary
| Measure | Time frame |
|---|---|
| Total Cholesterol. Timepoint: baseline and after 3th month. Method of measurement: in term of mg/ dL, by using biochemical kits.;LDL-C. Timepoint: baseline and after 3th month. Method of measurement: in term of mg/ dL, by using biochemical kits.;Body Fat Mass. Timepoint: baseline, at the end of 6th week and after 3th month. Method of measurement: in term of kg, by usig body analyser instrument.;Body Fat Free Mass. Timepoint: baseline, at the end of 6th week and after 3th month. Method of measurement: in term of kg, by usig body analyser instrument.;Body Mass Index (BMI). Timepoint: baseline, at the end of 6th week and after 3th month. Method of measurement: in term of kg/ m2.;Weight. Timepoint: baseline, at the end of 6th week and after 3th month. Method of measurement: in term of kg by using standardized scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSoheil Abbasi
Public Health faculty of Kermanshah University of Medical Science
Outcome results
None listed