Compare the supplemental fluid therapy before and during breast cancer surgery on post-operative nausea and vomiting and pain after cancer breast surgery.

Compare the effect of supplemental fluid therapy before and during breast cancer surgery on severity of post-operative nausea and vomiting and severity of pain.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201602116481N8

Enrollment

Registered

2016-03-01

Start date

2016-04-08

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer. Malignant neoplasm of breast

Interventions

Intervention 1: Intervention group 1: In this group, all of the patients beside the routine fluid therapy before and during breast cancer surgery, receive 5 cc/kg ringer-lactate serum from fasting tim

Prevention

Intervention group 1: In this group, all of the patients beside the routine fluid therapy before and during breast cancer surgery, receive 5 cc/kg ringer-lactate serum from fasting time until 2 hours

Control group: In this group all of patients receive routine fluid therapy before and during breast cancer surgery.

Intervention group 2: In this group, all of the patients beside the routine fluid therapy before and during breast cancer surgery, receive 5 cc/kg ringer-lactate serum during surgery.

Eligibility

Sex/Gender

Female

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age between 18-50 years; ASA (American Society of Anesthesiologists) physical status classification I and II. Exclusion criteria: History of smoking; renal or cardiac disorder; unusual bleeding during surgery; weight above 100 kg; uncontrolled hypertension.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Post-operative nausea and vomiting. Timepoint: 1, 4, 8, 24 hours after breast cancer surgery. Method of measurement: Post-operative nausea and vomiting questionnaire (Cortila).	—

Secondary

Measure	Time frame
Severity of pain. Timepoint: 1, 4, 8, and 24 hours after surgery. Method of measurement: Visual analog scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Soleimani

Semnan University of Medical Sciences

Soli257@yahoo.com+98 23 3344 1021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026