Condition 1: Patients with mild to moderate Alzheimer. Condition 2: Depressive. Alzheimer's disease, unspecified Major depressive disorder, single episode, unspecified
Conditions
Interventions
Intervention 1: Intervention group: In addition to receiving routine care, receive 5 cc of extract of fenugreek seed germ extract twice daily (equivalent to 3 grams of fenugreek seeds) for 4 months. T
Sponsors
Sabzevar University of Medical Sciences
Eligibility
Sex/Gender
All
Age
65 Months to 100 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Diagnose mild to moderate Alzheimer's disease based on CDR = 2. Complete the informed consent form.
Exclusion criteria
Exclusion criteria: Patients with evidence of other neurodegenerative disorders. Significant drug or alcohol misuse. Have a history of peptic ulcer. Use other complementary and alternative medicine methods during the study. Have sensetivity to fenugreek. Have allergic to peanuts, soybeans and peas. Use MAO Inh drugs. Have an acute disease in heart or liver or kidneys.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Short term and long term memory level. Timepoint: Measuring memory score at baseline (before intervention)and every month up to 4 months. Method of measurement: Clinical dementia rating. | — |
Secondary
| Measure | Time frame |
|---|---|
| Total antioxidant lab exams. Timepoint: 2 Stage. Method of measurement: Blood test for ransod kit manufactured by Randox, UK, Cat No. NX 2331, spectrophotometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzam Zarghi
Sabzevar University of Medical Sciences
Outcome results
None listed