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The effect of mucoadhesive polymer gel containing chlorhexidine %0.2 in the prevention of ventilator-associated pneumonia

Comparison of mucoadhesive polymer gel containing chlorhexidine %0.2 and the solution of chlorhexidine%0.2 in the prevention of ventilator-associated pneumonia in patients who admitted in intensive care unit

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201602095363N9
Enrollment
64
Registered
2016-12-21
Start date
2016-03-19
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator Associated Pneumonia. Pneumonitis due to other solids and liquids

Interventions

Intervention 1: The first group 5 ml chlorhexidine 0.2% product of Behsa pharmaceutical company which will be produced to mucoadhesive form by the School of Pharmacy of Zanjan University of Medical Sc
Treatment - Drugs
The first group 5 ml chlorhexidine 0.2% product of Behsa pharmaceutical company which will be produced to mucoadhesive form by the School of Pharmacy of Zanjan University of Medical Sciences as mouthw
The control group 5 ml oral solution containing chlorhexidine %0.2 product of Behsa pharmaceutical company as mouthwash will be received three times a day

Sponsors

Vice- Chancellor for Research of Zanjan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age between 20 and 50 years, Intubated patients and under mechanical ventilation, patients who have tooth, patients who are not pregnant, patients who have not Tracheostomy or T tube, Do not feeding from jejunostomy, don't have parental feeding. exclusion criteria: Admission less than one week, Death in less than 7 days after intubation,Extubation in less than 7 days

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Ventilator Associated Pneumonia. Timepoint: Third day, Sixth day, Ninth day, The twelfth day. Method of measurement: Clinical Pulmonary Infection Score.

Secondary

MeasureTime frame
Connection to ventilator days. Timepoint: End of the study. Method of measurement: Records.;Length of Intensive Care Unit stay. Timepoint: End of the study. Method of measurement: Records.;Mortality during hospitalization in Intensive Care Unit. Timepoint: End of the study. Method of measurement: Records.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Zargar

Zanjan University of Medical Sciences

Zargar.ali@gmail.com+98 24 3313 0001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026