Female infertility. Female infertility associated with anovulation
Conditions
Interventions
Intervention 1: Intervention group: From 21 days of cycle before the IVF , will be start oral estradiol valerate with 2 mg daily and will continue to the next cycle until the second day of the next c
Treatment - Drugs
Intervention group: From 21 days of cycle before the IVF , will be start oral estradiol valerate with 2 mg daily and will continue to the next cycle until the second day of the next cycle.
ovarian s
Control group: The control group also entered the antagonist and the gonadotropin treatment cycle , without treatment with estradiol.
Sponsors
Vice Chancellor for Research and Technology University of medical sciences
Eligibility
Sex/Gender
Female
Age
19 Years to 42 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Women 19 to 42 years old with low ovarian reserve; Women who have not responded to treatment with short antagonist protocol and gonadotropin or the number of oocytes has been equal to or less than 3. Exclusion criteria: who do not respond to treatment or have a cycle of follicle has been canceled; People who have certain diseases like hypothyroidism or hyper prolactin; If patients have complications such as embolism and contraindications to estrogen
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of mature follicles. Timepoint: 14 day of menstrual cycle. Method of measurement: Ultrasound.;Oocytes and embryos obtained count. Timepoint: 14 day of menstrual cycle. Method of measurement: Ultrasound. | — |
Secondary
| Measure | Time frame |
|---|---|
| Chemical and clinical pregnancy rate. Timepoint: After the delay period. Method of measurement: Tests and ultrasound.;The resulting embryo count. Timepoint: A month after a positive pregnancy test. Method of measurement: Ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Aliyeh Ghasemzadeh
Tabriz University of medical Sciences
Outcome results
None listed