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assesment of immunmodulatory effect of ß Glucan on wound healing in burn patients

assesment of immunmodulatory effect of ß Glucan on wound healing ,A two parallel group randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016020726411N1
Enrollment
124
Registered
2016-03-14
Start date
2016-04-08
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Burn wound. Condition 2: Burn wound.

Interventions

Intervention 1: The patients divide two groups: The first one is control group that receive the usual wound care protocol (silver sulfadiazine). Intervention 2: The second group comprising patients th
Treatment - Drugs
The patients divide two groups: The first one is control group that receive the usual wound care protocol (silver sulfadiazine)
The second group comprising patients that receive extracted beta Glucan in local form plus silver ointment

Sponsors

Ministry of Research and Technology Iran University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: According the similar studies in wound healing by using other imperious agents and attitude skin healing physician in motahari hospital, in this study inclusion criteria are;the age of patients:18-50 years.burn classification: second level and <50% of body surface is burned.Gender;two gender(male , famale) Exclusion criteria: the women with pregnancy; the patients with immunodeficiency, immunosuppression drug consumption; acute infections ;Liver and Kidney diseases .The pateints don’t permit to enter the other clinical trial during this study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Decrease at least 25% wound surface. Timepoint: decreasing the wound size in first week of care,the third day and end of second week and finally end of treatment. Method of measurement: centimeter.

Secondary

MeasureTime frame
TNF Alpha. Timepoint: End of study(8th week). Method of measurement: ELISA and OD.;IFN gamma. Timepoint: End of study(8th week). Method of measurement: ELISA and OD.;IL1. Timepoint: End of study(8th week). Method of measurement: ELISA and OD.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Maryam Roudbary

Iran university of Medical science

m_roudbary@yahoo.comroudbari.mr@iums.ac.ir+98 21 8670 3296

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026