Compare psychological and pharmacological treatment of generalized anxiety disorder

Comparative effects of cognitive behavioral therapy focused on intolerance of uncertainty and pharmacotherapy among patients with generalized anxiety disorder

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016020626397N1

Enrollment

Registered

2016-03-06

Start date

2016-01-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety. Generalized anxiety disorder

Interventions

Intervention 1: Type of intervention: a cognitive behavioral intervention group (intervention intolerance of uncertainty) is carried out which consists of twelve weekly 60-minute sessions. Interventi

Behavior

Treatment - Drugs

Type of intervention: a cognitive behavioral intervention group (intervention intolerance of uncertainty) is carried out which consists of twelve weekly 60-minute sessions.

Control group: group medication (anti-anxiety medications appropriate dose, under the Psychiatric) is performed.

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 18 and 35 years old; female gender; diagnosis of GAD according to DSM-5 criteria, and that so far have not received any treatment, including psychological and medical treatments. Exclusion criteria: comorbidity with other mental disorders; psychotic symptoms (hallucinations, delusions); having a physical illness.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Anxiety. Timepoint: Before the intervention, after the intervention and 1 month after intervention. Method of measurement: Beck Anxiety Inventory.	—

Secondary

Measure	Time frame
Intolerance of Uncertainty. Timepoint: Before the intervention, after the intervention and 1 month after intervention. Method of measurement: Intolerance of Uncertainty Scale.;Worry. Timepoint: Before the intervention, after the intervention and 1 month after intervention. Method of measurement: Penn State Worry Questionnaire-Why Worry-II-Questionnaire.;Cognitive Avoidance. Timepoint: Before the intervention, after the intervention and 1 month after intervention. Method of measurement: Cognitive Avoidance Questionnaire.;Negative Problem Orientation. Timepoint: Before the intervention, after the intervention and 1 month after intervention. Method of measurement: Negative Problem Orientation Questionnaire.	—

Measure

Time frame

Intolerance of Uncertainty. Timepoint: Before the intervention, after the intervention and 1 month after intervention. Method of measurement: Intolerance of Uncertainty Scale.;Worry. Timepoint: Before the intervention, after the intervention and 1 month after intervention. Method of measurement: Penn State Worry Questionnaire-Why Worry-II-Questionnaire.;Cognitive Avoidance. Timepoint: Before the intervention, after the intervention and 1 month after intervention. Method of measurement: Cognitive Avoidance Questionnaire.;Negative Problem Orientation. Timepoint: Before the intervention, after the intervention and 1 month after intervention. Method of measurement: Negative Problem Orientation Questionnaire.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNegar Beheshti

University of Kurdistan

ne.beheshti@gmail.com+98 83 3835 4502

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026