Probiotics and children under hemodialysis treatment

Evaluation of the Efficacy of Probiotic Supplementation on bio-markers of inflammation and oxidative stress in pediatric patients under treatment with hemodialysis: randomized double blind clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160206026390N11

Enrollment

Registered

2019-06-10

Start date

2018-12-22

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric under hemodialysis treatment. Chronic kidney disease (CKD)

Interventions

Intervention 1: Intervention group: Probiotic Intervention group receive probiotics Probiotic contain following strains : Lactobacillus casei ?Lactobacillus acidophilus ? Lactobacillus rhamnosus ? L

Eligibility

Sex/Gender

All

Age

4 Years to 18 Years

Inclusion criteria

Inclusion criteria: Hemodialysis Patients during study period Two weeks after Discontinue antibiotics Two weeks after resolving acute inflammatory settings Two weeks after Discontinue probiotics

Exclusion criteria

Exclusion criteria: Patients with Chronic Inflammatory Setting like glumerolonephritis or nephrotic syndrome Patients received antibiotic or under inflammatory setting like polmunary infection or gastroenteritis Candidate for transplantation Receiving immuno-suppressive drugs specially steroids Receiving probiotics for any reason

Design outcomes

Primary

Measure	Time frame
Total Antioxidant Capacity. Timepoint: before and after intervention. Method of measurement: ELISA.;Nuclear Factor-kappa B. Timepoint: before and after intervention. Method of measurement: ELISA.;Vascular cell adhesion molecule - 1. Timepoint: before and after intervention. Method of measurement: ELISA.	—

Secondary

Measure	Time frame
. Timepoint: . Method of measurement: .;. Timepoint: . Method of measurement: .	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMitra Naseri

Mashhad University of Medical Sciences

NaseriM@mums.ac.ir+98 51 3841 2081

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026