Effects of oral administration of cinnamon on rheumatoid arthritis

The effect of cinnamon on the clinical signs, fasting blood sugar , lipid profile , liver enzymes , blood pressure and inflammatory markers in women with rheumatoid arthritis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016020414680N3

Enrollment

Registered

2016-02-13

Start date

2016-04-02

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Active Rheumatoid Arthritis. Other specified rheumatoid arthritis

Interventions

Intervention 1: intervention group:Four cinnamon capsules 500 mg daily for 8 week. Intervention 2: The placebo group:Four placebo daily for 8 weeks.

Placebo

intervention group:Four cinnamon capsules 500 mg daily for 8 week

The placebo group:Four placebo daily for 8 weeks

Eligibility

Sex/Gender

Female

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Diagnosis of rheumatoid arthritis According to American College Rheumatology criteria (ACR) -Female gender-Age over 18 years-The disease duration for at least two years-Having active disease- Exclusion criteria:Rejection of cinnamon capsules(the receptionless than 80 %)-Developing sudden acute illness?Immigration?Any change in treatment protocol and drugs that led to the removal of the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
CRP. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Latex method.;TNF-a. Timepoint: Before and after 8 weeks of intervention. Method of measurement: ELISA.;Systolic blood pressure. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Barometer.;Diastolic blood pressure. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Barometer.;Triglyceride. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Enzymatic Method.;Total cholesterol. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Enzymatic Method.;HDL cholesterol. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Enzymatic Method.;LDL cholesterol. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Fried-Wald formula.;Fasting blood sugar. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Colorimetric method.;ALT. Timepoint: Before and after 8 weeks of intervention. Method of measurement: UV tes.;AST. Timepoint: Before and after 8 weeks of intervention. Method of measurement: UV test.;ESR. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Westergren.;Disease activity score. Timepoint: Before and after 8 weeks of intervention. Method of measurement: DAS-28 questionnaire.	—

Measure

Time frame

CRP. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Latex method.;TNF-a. Timepoint: Before and after 8 weeks of intervention. Method of measurement: ELISA.;Systolic blood pressure. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Barometer.;Diastolic blood pressure. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Barometer.;Triglyceride. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Enzymatic Method.;Total cholesterol. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Enzymatic Method.;HDL cholesterol. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Enzymatic Method.;LDL cholesterol. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Fried-Wald formula.;Fasting blood sugar. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Colorimetric method.;ALT. Timepoint: Before and after 8 weeks of intervention. Method of measurement: UV tes.;AST. Timepoint: Before and after 8 weeks of intervention. Method of measurement: UV test.;ESR. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Westergren.;Disease activity score. Timepoint: Before and after 8 weeks of intervention. Method of measurement: DAS-28 questionnaire.

—

Secondary

Measure	Time frame
Body mass index. Timepoint: Before and after 8 weeks of intervention. Method of measurement: Calculation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarideh Shishebor

Ahvaz Jundishapour University of Medical Sciences

shishehbor-f@ajums.ac.ir+98 61 3373 8319

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026