Effect of implementing local cooling in different times versus no implementation on pain severity and extend of bruise due to subcutaneous enoxaparin injection in cardiovascular patients

Effect of implementing local cooling in different times versus no implementation on pain severity and extend of bruise due to subcutaneous enoxaparin injection in cardiovascular patients: a randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201602029014N92

Enrollment

150

Registered

2016-02-11

Start date

2016-02-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain. Pain, unspecified

Interventions

Intervention 1: ocal cooling using ice bag for 180 seconds 5 minutes before subcutaneous enoxaparin injection. Intervention 2: local cooling using ice bag for 180 seconds immediately after subcutaneou

Prevention

ocal cooling using ice bag for 180 seconds 5 minutes before subcutaneous enoxaparin injection

local cooling using ice bag for 180 seconds immediately after subcutaneous enoxaparin injection

Subcutaneous enoxaparin injection without any intervention

Eligibility

Sex/Gender

All

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: (a) age of 30 to 70 years; (b) indication of subcutaneous enoxaparin injection for the first time; (c) conscious and ability to percept and state the pain. Exclusion criteria: (a) receiving analgesic within past 4 hours; (b) death or discharge during 72 hours; (c) coagulopathy; (d) using anticoagulant agents.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Measuring pain severity. Timepoint: immediately after injection. Method of measurement: using visual analog scale.	—

Secondary

Measure	Time frame
Measuring extend of bruise. Timepoint: 12, 24, and 48 hours after injection. Method of measurement: using ruler.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMostafa Najafi

Farshchian Hospital

mostafanajafi115@gmail.com+98 81 3827 4184

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026